Chin-Down Posture vs Thickened Liquid Diet for Aspiration Prevention in Parkinson's Disease and Dementia
Chin-down position
+ Thickened liquid administration
Synucleinopathies+21
+ Basal Ganglia Diseases
+ Mental Disorders
Prevention Study
Summary
This study focuses on finding the best way to prevent liquid aspiration and aspiration pneumonia in patients with Parkinson's disease and/or dementia. Liquid aspiration is common in older populations, particularly those dealing with debilitation, dementia, and depression. It can lead to pneumonia, which is a significant cause of death in the US among individuals aged 65 and over. Currently, two methods are used to manage this issue: chin-down posture during swallowing and the use of thickened liquids in the diet. However, there's no clear evidence favoring one method over the other, which is why this research is important. In this Phase III study, participants are randomly assigned to either the chin-down position group or the thickened liquid diet group, based on their swallowing function during a modified barium swallow test. The study will recruit patients over a three-year period, with each patient's participation lasting no more than three months. The study aims to determine which of these two interventions is more effective in preventing aspiration and aspiration pneumonia.
Protocol
This section provides details of the study plan, including how the study is designed and what the study is measuring.600 patients to be enrolled
Total number of participants that the clinical trial aims to recruit.Prevention Study
Eligibility
Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.Any sex
Biological sex of participants that are eligible to enroll.From 50 to 95 Years
Range of ages for which participants are eligible to join.Healthy volunteers not allowed
If individuals who are healthy and do not have the condition being studied can participate.Conditions
Pathology
Criteria
Study Centers
These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.This study has 1 location
University of Wisconsin at Madison & multiple other U.S. locations
Madison, United StatesOpen University of Wisconsin at Madison & multiple other U.S. locations in Google Maps