Completed

Effects of Nefazodone on Treatment of Female Cocaine Abusers

What is being tested

Data Collection

Who is being recruted

Mental Disorders+1

+ Substance-Related Disorders

+ Cocaine-Related Disorders

From 18 to 55 Years

See all eligibility criteria

How is the trial designed

Treatment Study

Phase 2

Interventional

Study Start: December 1996

See protocol details

Summary

Principal SponsorNational Institute on Drug Abuse (NIDA)

Last updated: January 27, 2026

Sourced from a government-validated database.Claim as a partner

Study start date: December 1, 1996

Actual date on which the first participant was enrolled.

This study evaluated the effect of nefazodone on reducing cocaine use and craving in both depressed and nondepressed women and if there was a greater effect in depressed women.

Official TitleEffects of Nefazodone on Treatment of Female Cocaine Abusers

NCT00000286

Principal SponsorNational Institute on Drug Abuse (NIDA)

Last updated: January 27, 2026

Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.

Treatment Study

These studies test new ways to treat a disease, condition, or health issue. The goal is to see if a new drug, therapy, or approach works better or has fewer side effects than existing options.

Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.

Conditions

Criteria

Female

Biological sex of participants that are eligible to enroll.

From 18 to 55 Years

Range of ages for which participants are eligible to join.

Healthy volunteers not allowed

If individuals who are healthy and do not have the condition being studied can participate.

Conditions

Pathology

Mental DisordersSubstance-Related DisordersCocaine-Related DisordersChemically-Induced Disorders

Criteria

Inclusion Criteria: Females, ages 18-55, minimum use of 8 days of the last 30, minimum of 8th grade education, current diagnosis of cocaine abuse/dependence Exclusion Criteria: Unstable medical illness, dx of MR, OBS, bipolar

Study Plan

Find out more about all the medication administered in this study, their detailed description and what they involve.

Study Objectives

Primary Objectives

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 1 location

Suspended

University of Minnesota

Minneapolis, United StatesOpen University of Minnesota in Google Maps

CompletedOne Study Center