Completed

Effects of Alcohol History on Effects of Sevoflurane and Nitrous Oxide

What is being tested

30% Nitrous oxide

+ Placebo

+ 0.2% sevoflurane

DrugOther

Who is being recruted

Narcotic-Related Disorders+3

+ Mental Disorders

+ Opioid-Related Disorders

See all eligibility criteria

How is the trial designed

Phase 2

Interventional

Study Start: November 1997

See protocol details

Summary

Principal SponsorUniversity of Chicago

Last updated: January 27, 2026

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Study start date: November 1, 1997

Actual date on which the first participant was enrolled.

The purpose of this study is to evaluate the effects of alcohol history on the subjective and reinforcing effects of sevoflurane and nitrous oxide in healthy volunteers. All subjects underwent psychomotor testing during 4 sessions of placebo, drug/placebo, and choice of intervention.

Official TitleEffects of Alcohol History on Effects of Sevoflurane and Nitrous Oxide

NCT00000261

Principal SponsorUniversity of Chicago

Last updated: January 27, 2026

Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.

Design Details

14 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.

Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.

Conditions

Criteria

Any sex

Biological sex of participants that are eligible to enroll.

Healthy volunteers not allowed

If individuals who are healthy and do not have the condition being studied can participate.

Conditions

Pathology

Narcotic-Related DisordersMental DisordersOpioid-Related DisordersSubstance-Related DisordersAlcohol-Related DisordersChemically-Induced Disorders

Criteria

Please contact site for information.

Study Plan

Find out more about all the medication administered in this study, their detailed description and what they involve.

Treatment Groups

Study Objectives

One single intervention group is designated in this study

This study does not include a placebo group

Treatment Groups

Group I

Experimental

Study Objectives

Primary Objectives

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 1 location

Suspended

University of Chicago, Anesthesia & Critical Care

Chicago, United StatesOpen University of Chicago, Anesthesia & Critical Care in Google Maps

CompletedOne Study Center