Completed

Prednisone Treatment for Alzheimer's Disease

0 criteria met from your profileSee at a glance how your profile meets each eligibility criteria.
What is being tested

Prednisone

Drug
Who is being recruted

Mental Disorders+6

+ Brain Diseases

+ Central Nervous System Diseases

+2 Eligibility Criteria
See all eligibility criteria
How is the trial designed

Treatment Study

Phase 3
Interventional
See protocol details

Summary

Principal SponsorNational Institute on Aging (NIA)
Last updated: June 24, 2005
Sourced from a government-validated database.Claim as a partner

The study focuses on exploring the potential benefits of Prednisone, a type of medication, in managing Alzheimer's Disease. This research is designed for individuals diagnosed with Alzheimer's, aiming to understand if Prednisone can improve their condition. The importance of this trial lies in its potential to uncover new treatment options for Alzheimer's, a disease currently without a cure. In this study, participants are randomly assigned to two groups - one receives Prednisone while the other receives a placebo, a substance with no therapeutic effect. Neither the participants nor the researchers know who gets which, ensuring unbiased results. The participation lasts for 68 weeks, during which individuals need to visit the clinic 15 times. Participants are required to take Prednisone or the placebo daily, with the highest dose being 20 mg, along with calcium and vitamin supplements.

NCT00000178
Principal SponsorNational Institute on Aging (NIA)
Last updated: June 24, 2005
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.

Treatment Study

These studies test new ways to treat a disease, condition, or health issue. The goal is to see if a new drug, therapy, or approach works better or has fewer side effects than existing options.

Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Conditions
Criteria

Any sex

Biological sex of participants that are eligible to enroll.

Healthy volunteers not allowed

If individuals who are healthy and do not have the condition being studied can participate.

Conditions

Pathology

Mental DisordersBrain DiseasesCentral Nervous System DiseasesDementiaNervous System DiseasesNeurodegenerative DiseasesNeurocognitive DisordersTauopathiesAlzheimer Disease

Criteria

1 inclusion criteria required to participate
Patients with Alzheimer's disease who are in stable medical condition
1 exclusion criteria prevent from participating
Patients with diabetes or severe osteoporosis

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 19 locations

University of Alabama, Birmingham

Birmingham, United StatesOpen University of Alabama, Birmingham in Google Maps

University of Southern California

Los Angeles, United States

University of California, San Diego

San Diego, United States

Mayo Clinic Jacksonville

Jacksonville, United States
Completed19 Study Centers