Silicone Oil vs Gas Tamponade in Retinal Detachment Treatment
Data Collection
Eye Diseases+1
+ Retinal Detachment
+ Retinal Diseases
Treatment Study
Summary
Study start date: September 1, 1985
Actual date on which the first participant was enrolled.Retinal detachment complicated by PVR can be challenging to treat. While some cases respond well to pars plana vitrectomy and temporary support from intraocular gas, others may redetach. Preliminary findings suggest that prolonged support with liquid silicone can improve success rates, but there may be complications such as glaucoma and keratopathy. This study aims to compare the benefits of silicone oil versus gas as support methods in this procedure. It focuses on two groups: those who haven't had a prior vitrectomy (Group 1) and those who have (Group 2). The goal is to find a more effective and safer treatment approach for this condition. During the study, all participants undergo vitrectomy and are randomly assigned to receive either silicone oil or gas. The surgical procedure is standardized to relieve retinal traction, and the eye's response is assessed using an intraocular air support. The assignment to silicone oil or gas only happens after the surgical procedure to avoid any bias. Participants are then examined multiple times over a 36-month period, with repeat surgery allowed if necessary. The study's end points are visual acuity of 5/200 or greater and macular reattachment for 6 months following the final surgery. The success rates and complication rates of the two support methods are then compared.
Protocol
This section provides details of the study plan, including how the study is designed and what the study is measuring.Treatment Study
Eligibility
Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.Any sex
Biological sex of participants that are eligible to enroll.Healthy volunteers not allowed
If individuals who are healthy and do not have the condition being studied can participate.Conditions
Pathology
Criteria
Eligibility criteria included but were not limited to PVR of Grade C-3 or greater according to the Retina Society Classification and visual acuity of light perception or better.