Completed

Impact of Dietary Fat and Endurance Running on Intramuscular Lipid Stores

0 criteria met from your profileSee at a glance how your profile meets each eligibility criteria.
What is being tested

Data Collection

Who is being recruted

Behavior+7

+ Body Weight

+ Motor Activity

From 18 to 49 Years
+4 Eligibility Criteria
See all eligibility criteria
How is the trial designed

Treatment Study

Interventional
See protocol details

Summary

Principal SponsorNational Center for Research Resources (NCRR)
Last updated: January 27, 2026
Sourced from a government-validated database.Claim as a partner

This study focuses on understanding how diet and endurance running affect fat stores within muscles, using a technique called 1 H Magnetic Resonance Spectroscopy (MRS). The research involves endurance-trained athletes and aims to explore how a prolonged running session impacts these fat stores, and how they replenish afterwards when following either a low-fat or moderate-fat diet. The importance of this study lies in its potential to shed light on how dietary fat influences the health and performance of individuals engaged in intense physical training. The findings could also contribute to obesity research, helping to understand relationships between muscle fat stores, insulin resistance, and obesity. Participants in this study are endurance athletes who will undergo a 2-hour training run. After this, they will follow two different diets - one with very low fat content (10% of energy from fat) and another with moderate fat content (35% of energy from fat). The order of the diets is randomly assigned. The study measures the change in muscle fat stores after the run and during recovery, while following each diet. The researchers believe that prolonged exercise will decrease muscle fat stores, and that a low-fat diet may slow down their replenishment compared to a moderate-fat diet.

Official TitleInfluence of Diet and Endurance Running on Intramuscular Lipids Measured at 4.1 TESLA
NCT00000110
Principal SponsorNational Center for Research Resources (NCRR)
Last updated: January 27, 2026
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.

Treatment Study

These studies test new ways to treat a disease, condition, or health issue. The goal is to see if a new drug, therapy, or approach works better or has fewer side effects than existing options.

Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Conditions
Criteria

Any sex

Biological sex of participants that are eligible to enroll.

From 18 to 49 Years

Range of ages for which participants are eligible to join.

Healthy volunteers allowed

If individuals who are healthy and do not have the condition being studied can participate.

Conditions

Pathology

BehaviorBody WeightMotor ActivityNutrition DisordersNutritional and Metabolic DiseasesObesitySigns and SymptomsPathological Conditions, Signs and SymptomsOvernutritionOverweight

Criteria

4 inclusion criteria required to participate
Healthy volunteers (developmental phase)

Healthy endurance-trained subjects

Maximum age for males is 39

Maximum age for females is 49

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 1 location

Suspended

The University of Alabama at Birmingham Nutrition Sciences Department

Birmingham, United StatesOpen The University of Alabama at Birmingham Nutrition Sciences Department in Google Maps
CompletedOne Study Center