Completed

Body Composition and Resting Metabolic Rates in Adults with Cyanotic Congenital Heart Disease

0 criteria met from your profileSee at a glance how your profile meets each eligibility criteria.
What is being collected

Data Collection

Who is being recruted

Congenital Abnormalities+3

+ Cardiovascular Diseases

+ Heart Defects, Congenital

From 17 to 60 Years
1 Eligibility Criteria
See all eligibility criteria
How is the trial designed

Case-Control

Comparing exposures between individuals with and without disease in order to identify potential risk factors.
Observational
See protocol details

Summary

Principal SponsorNational Center for Research Resources (NCRR)
Last updated: January 27, 2026
Sourced from a government-validated database.Claim as a partner

This study focuses on adults with cyanotic congenital heart disease, a condition where the heart doesn't pump enough oxygen to the body due to a birth defect. These adults often have high levels of a substance called plasma proatrial natruretic peptide (proANP), which may cause chronic dehydration. This can lead to less oxygen reaching the tissues and cause shortness of breath during activity. The main goal of this study is to understand the body composition, specifically water and fat-free mass, and the resting metabolic rates in adults with this heart condition. The study aims to include adults with cyanotic congenital heart disease and healthy adults of the same age, gender, and body weight for comparison. The study's findings could help improve the care and management of this heart condition. During the study, participants will undergo several measurements to determine their body composition. This includes the amount of body water, fat, and lean tissue they have. The study will also measure how many calories the body uses when at rest. These measurements will provide valuable insights into the body's metabolism and hydration status in adults with cyanotic congenital heart disease. As this is an observational study, participants will not receive any treatment or intervention.

Official TitleBody Water Content in Cyanotic Congenital Heart Disease
NCT00000107
Principal SponsorNational Center for Research Resources (NCRR)
Last updated: January 27, 2026
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.

Case-Control

These studies compare people who have a disease (cases) with those who don't (controls). The goal is to look back at previous exposures or risk factors to identify what might have contributed to the disease.

Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Conditions
Criteria

Any sex

Biological sex of participants that are eligible to enroll.

From 17 to 60 Years

Range of ages for which participants are eligible to join.

Healthy volunteers allowed

If individuals who are healthy and do not have the condition being studied can participate.

Conditions

Pathology

Congenital AbnormalitiesCardiovascular DiseasesHeart Defects, CongenitalHeart DiseasesCongenital, Hereditary, and Neonatal Diseases and AbnormalitiesCardiovascular Abnormalities

Criteria

1 inclusion criteria required to participate
Resting blood pressure below 140/90

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 1 location

Suspended

University of Vermont

Burlington, United StatesOpen University of Vermont in Google Maps
CompletedOne Study Center
Body Composition and Resting Metabolic Rates in Adults with Cyanotic Congenital Heart Disease | PatLynk