Follow-up for Patients Previously Enrolled on the Center for Cancer Research Protocols

Background: Patients enrolled on CCR clinical protocols may require long term follow-up to assess outcome (e.g., survival) or the effects of prior therapy. Keeping the primary treatment protocols open after accrual is complete in order to follow patients for long term outcome is an administrative burden on investigators and the IRB. Objectives: -To provide follow-up for patients who are long term survivors previously enrolled Center for Cancer Research (CCR) trial but who may not currently be enrolled on a research protocol. Eligibility: -Patients who were previously enrolled on a CCR protocol and who are not eligible for an active NCI intramural primary research protocol. Design: The medical procedures/tests will be based on the patient's diagnosis, treatment and supporting clinical information. This is a follow-up study in which only standard tests and procedures are to be performed. Clinical information that is relevant to the patients prior protocols will be collected for research purposes. Procedures that entail more than minimal risk to the patient should not be performed for research purposes on this protocol.