Functional Brain Mapping of Planning Activities With [015] Water PET Blood Flow Technique
Collecte de données
Troubles Mentaux
+ Troubles Neurocognitifs
+ Troubles de la cognition
Résumé
Date de début de l'étude : 1 janvier 1993
Date à laquelle le premier participant a commencé l'étude.This protocol will attempt to determine the topographical distribution in the brain of the cognitive components of planning using the [150] water PET blood flow technique. We will administer perception, motor, simple decision, and planning tasks using the game of chess and the Tower of Hanoi Test as paradigms. Utilizing a "subtraction technique" we hope to identify those areas of cerebral cortex which are most activated by planning processes. It is predicted that the dorsolateral frontal areas will be most prominently activated. It is also predicted that the essential components of the planning process will be the same regardless of the type of plans being executed. The data we collect will be of value in determining 1) the neural representation of planning processes and 2) in guiding cognitive models of the planning system.
Protocole
Cette section fournit des détails sur le plan de l'étude, y compris la manière dont l'étude est conçue et ce qu'elle évalue.230 participants à inclure
Nombre total de participants que l'essai clinique vise à recruter.Éligibilité
Les chercheurs recherchent des patients correspondant à une certaine description appelée critères d'éligibilité : état de santé général ou traitements antérieurs du patient.Tout sexe
Le sexe biologique des participants éligibles à s'inscrire.Volontaires sains non autorisés
Indique si les individus en bonne santé et ne présentant pas la condition étudiée peuvent participer.Conditions
Pathologie
Critères
Normal Controls: Males and female subjects from two age ranges: 18-30 and 50-65 years of age. Individuals with a history of neurological or psychiatric disorder will not be included nor will individuals currently taking psychoactive medication. Patients: Patients with outstanding problems in planning. Patients must have a diagnosed CNS disorder with lesion localization verified by MRI scanning available from the referring physician or completed at the NIH Clinical Center. Patients with unilateral or bilateral lesions that meet the behavioral criteria for selection (planning disorder). Patients will be medication free (or taking medication with no known central nervous system effects) and be able to understand instructions and task demands.
Centres d'étude
Ce sont les hôpitaux, cliniques ou centres de recherche où l'essai est conduit. Vous pouvez trouver le site le plus proche de vous ainsi que son statut.Cette étude comporte 1 site
National Institute of Neurological Disorders and Stroke (NINDS)
Bethesda, United StatesOuvrir National Institute of Neurological Disorders and Stroke (NINDS) dans Google Maps