Continuous High-Dose Intravenous Dextran Sulfate in Human Immunodeficiency Virus-Infected Individuals

Inclusion Criteria Concurrent Medication: Allowed: * Acetaminophen. Patients must have: \- Clinically documented AIDS or AIDS-related complex (ARC) defined as CDC group IVA or history of any of the findings that define CDC group IV subgroup C-2: * oral candidiasis, oral hairy leukoplakia, multidermatomal herpes zoster, recurrent nontyphoidal Salmonella bacteremia, or nocardiosis. Prior Medication: Allowed: * Acetaminophen. Exclusion Criteria Concurrent Treatment: Excluded: * Intramuscular injections. Patients will be excluded from the study for the following reasons: * Acute illness requiring hospitalization or antiviral drug therapy for treatment. * Volunteers who have taken any antiviral medications, anticoagulants, antiplatelet medications, or any nonsteroidal anti-inflammatory drugs, except acetaminophen, within 2 weeks of study entry, or those who anticipate the need for such medication during the study. * Positive stool guaiac at screening. * Disorders of coagulation or any known contraindication to anticoagulation, including but not limited to gastrointestinal or other serious bleeding, major trauma or surgery within the past 2 months, stroke or suspicion of central nervous system (CNS) bleeding, Kaposi sarcoma (with or without proven gastrointestinal involvement), and any known CNS lesions that might be prone to bleed. * Allergy to dextran sulfate or heparin. * Acute or asymptomatic HIV infection. Prior Medication: Excluded: * Antiviral medications. * Anticoagulants. * Antiplatelet medications. * Any nonsteroidal anti-inflammatory drugs (except acetaminophen). Prior Treatment: Excluded: * Hospitalization for acute illness. Patients may not have any of the following diseases or symptoms: * Allergy to dextran sulfate or heparin. * Acute or asymptomatic HIV infection. * Acute illness requiring hospitalization. * Chronic anemia requiring transfusion within the past month. * Disorders of coagulation or any known contraindication to anticoagulation, including but not limited to gastrointestinal or other serious bleeding, major trauma or surgery within the past 2 months, stroke or suspicion of central nervous system (CNS) bleeding, Kaposi's sarcoma, and any known CNS lesions which might be prone to bleed.