Longitudinal Evaluation of Keratoconus Progression and Patient Quality of Life
Collecte de données
Données recueillies dès le début de l'étude - ProspectiveMaladies cornéennes
+ Maladies oculaires
+ Kératocône
Résumé
Date de début de l'étude : 1 juin 1995
Date à laquelle le premier participant a commencé l'étude.Keratoconus is a condition that affects the cornea, the clear front part of the eye. It causes the cornea to thin and bulge out, leading to distorted vision. People with keratoconus often need glasses or rigid contact lenses to see clearly, and some may even require a corneal transplant. The condition typically affects individuals during their prime earning years and significantly impacts their lives. The Collaborative Longitudinal Evaluation of Keratoconus (CLEK) Study aims to better understand how this disease progresses and what factors might influence its severity. By doing so, it hopes to provide answers to common patient questions and improve the overall management of this complex eye condition. The CLEK Study is observing 1,209 patients with keratoconus over a period of 3 years. Participants undergo annual examinations at 15 different clinical centers. These check-ups include tests to measure visual acuity, assess the quality of life, capture images of the cornea, examine the fit of contact lenses, and evaluate the overall health of the eye. The study does not involve any treatment, but rather collects information to better understand the disease. The findings from this study will help eye care practitioners manage keratoconus more effectively and provide patients with a clearer understanding of what to expect from their condition.
Protocole
Cette section fournit des détails sur le plan de l'étude, y compris la manière dont l'étude est conçue et ce qu'elle évalue.Éligibilité
Les chercheurs recherchent des patients correspondant à une certaine description appelée critères d'éligibilité : état de santé général ou traitements antérieurs du patient.Tout sexe
Le sexe biologique des participants éligibles à s'inscrire.À partir de 12 ans
Tranche d'âge des participants éligibles à participer.Volontaires sains non autorisés
Indique si les individus en bonne santé et ne présentant pas la condition étudiée peuvent participer.Conditions
Pathologie
Critères
Patients with keratoconus were eligible if they were at least 12 years old; had an irregular cornea as determined by keratometry, retinoscopy, or direct ophthalmoscopy in at least one eye; had Vogt's striae, Fleischer's ring, or corneal scarring characteristic of keratoconus in at least one eye; and planned to stay in the area for at least 3 years. They were ineligible if they had bilateral corneal transplants or bilateral nonkeratoconic eye disease (cataract, intraocular lenses, macular disease, or optic nerve disease other than glaucoma).
Centres d'étude
Ce sont les hôpitaux, cliniques ou centres de recherche où l'essai est conduit. Vous pouvez trouver le site le plus proche de vous ainsi que son statut.Cette étude comporte 14 sites
University of California, Berkeley, School of Optometry
Berkeley, United StatesOuvrir University of California, Berkeley, School of Optometry dans Google MapsSouthern California College of Optometry
Fullerton, United StatesJules Stein Eye Institute, University of California at Los Angeles
Los Angeles, United StatesNova Southeastern University, Health Professions Division, College of Optometry
Fort Lauderdale, United States