Efectos de las estatinas y el ejercicio en la salud de pacientes con dislipidemia

Atorvastatin 80mg

Exercise

Atorvastatin 80mg

Exercise

Citrate synthase maximal activity (µmol/g/min)

Fasting plasma glucose (mmol/L)

Maximal 3-hydroxy-acetylCoa-dehydrogenase activity (µmol/g/min).

Concentration of glycosylated hemoglobin A1c (HbA1c) (mmol/mol)

Maximal oxygen uptake (ml/min)

Targeted skeletal muscle proteomics

Lipid profile (mmol/L)

Concentration of lipoprotein (a) (nmol/L)

Concentration of apolipoprotein B (nmol/L)

Statins (atorvastatin) accumulation in muscle tissue

Skeletal muscle coenzyme Q10

Body weight (kg)

Blood pressure (mmHg)

Resting heart rate (bpm)

Steady-state systemic oxygen uptake (mL/min)

Quality of life score

Maximal phosphofructokinase activity (µmol/g/min)

Waist and hip circumference (cm)

Hand-grip strength (kg)

Mitochondrial expression of complex I (arbitrary units)

HOMA-IR

Matsuda Index

Insulin secretion rate (ISR)

Oral disposition index

Statin-associated muscle symptoms (SAMS)

Statin-associated muscle symptoms (SAMS)

Statin-associated muscle symptoms (SAMS)

Statin-associated muscle symptoms (SAMS)

Mitochondrial expression of complex II (arbitrary units)

Mitochondrial expression of complex III (arbitrary units)

Mitochondrial expression of complex IV (arbitrary units)

Mitochondrial expression of complex V (arbitrary units)

Change in plasma Apolipoprotein H concentration mg/dL (or g/L)

Change in plasma Clusterin (Apo J) concentration mg/dL (or g/L)

Apolipoprotein M concentration mg/dL (or g/L)

Change in plasma Apolipoprotein A-I concentration mg/dL (or g/L)

Change in plasma Apolipoprotein A-II concentration mg/dL (or g/L)

Change in plasma Apolipoprotein A-IV concentration mg/dL (or g/L)

Change in plasma Apolipoprotein B-100 concentration mg/dL (or g/L)

Change in plasma Apolipoprotein B-48 concentration mg/dL (or g/L)

Change in plasma Apolipoprotein C-II concentration mg/dL (or g/L)

Change in plasma Apolipoprotein C-III concentration mg/dL (or g/L)

Change in plasma Apolipoprotein D concentration mg/dL (or g/L)

Change in plasma Apolipoprotein E concentration mg/dL (or g/L)

Change in plasma Cholesteryl Ester Transfer Protein (CETP) activity µmol cholesteryl-ester transferred · min-¹ · L-¹ (or "units /L")

Change in plasma Lecithin-Cholesterol Acyltransferase (LCAT) activity nmol cholesteryl-ester formed · min-¹ · mL-¹

Change in plasma Albumin concentration (g/dL)

Change in plasma Transthyretin concentration (mg/dL)

Body fat percentage (%)

Lean body mass (kg)