Combined Exercise and Nutrition Intervention for Possible Sarcopenia Among Community-dwelling Older Adults in Primary Care: A Randomized Controlled Trial

Fecha de inicio: 8 de agosto de 2023

Inclusion Criteria: * 65 to 85 years of age * Men and women with possible sarcopenia * If included in the possible sarcopenia criteria in the 2019 Asian Working Group for Sarcopenia(AWGS) criteria A Simple Questionnaire to Rapidly Diagnose Sarcopenia(The Korean SARC-F questionnaire) score is 4 or higher; or Calf circumference (Men's: \<34 cm, Women's: \<33 cm) + Decreased muscle strength (male: \<28kg, female: \<18kg) or Decreased physical function (if it takes more than 12 seconds from the 5-chair stand test) * \[(1) and {(2) or (3)}\] Exclusion Criteria: * Renal failure: Serum creatine exceeding 2.0 mg/dl * Uncontrolled hypertension: systolic/diastolic blood pressure greater than 150/90 millimeter of mercury(mmHg) * Uncontrolled diabetes: glycated hemoglobin (HbA1C) over 7.5% * Subject who are receiving treatment (steroids, anticancer drugs, etc.) that can affect muscle mass * Subjects with myocardial infarction or angina pectoris, stroke disease * Malignant tumor: Subject who has a history of cancer within 5 years or is currently receiving treatment * Subjects who have liver cirrhosis and uncontrolled hepatitis (Aspartate aminotransferase or Alanine aminotransferase is more than three times the upper limit of the reference range) * Subjects who have chronic diseases such as musculoskeletal disorders that are impossible to exercise * Subjects who are allergic to soybeans, coix, and brown rice