NUTSNUTS for the Prevention of Cardiovascular Disease in Chinese Adults : a Randomized Controlled Trial (NUTS)

Fecha de inicio: 14 de octubre de 2019

Inclusion Criteria: 1. A history of CVD, defined on the basis of a prior hospitalisation for a myocardial infarction or stroke, unstable angina, coronary artery bypass graft, percutaneous coronary intervention (with or without stenting), peripheral revascularization (angioplasty or surgery), symptomatic with documented hemodynamically-significant carotid or peripheral vascular disease, or amputation secondary to vascular disease, OR 2. Male aged \>60 years, or female aged\>65 years, AND With at least two of the following risk factors: 1. Type 2 diabetes requiring treatment with at least two oral anti-hyperglycaemic agents and/or insulin 2. Systolic blood pressure \> 140 mmHg while on one or more antihypertensive agents 3. Current daily smoking 4. Dyslipidaemia defined as HDL-cholesterol\<1.0mmol/L or LDL-cholesterol\>6.0mmol/L 5. Micro or macro albuminuria Exclusion Criteria: 1. Allergic to nuts (history of food allergy with hypersensitivity to any of the components of nuts) 2. Other serious medical condition that prevents nut consumption (e.g. digestive disease with fat intolerance) 3. Any medical condition thought to limit survival to less than 1 year 4. Difficulty with consuming nuts (e.g. dental health issues that prevent chewing walnuts) 5. Unwilling to consume nuts