Comprehensive Rehabilitation Program Versus Traditional Chest Physiotherapy for Weaning From Mechanical Ventilator

This study focuses on improving the weaning process from mechanical ventilators for critically ill patients. Prolonged immobility in the ICU can lead to functional losses, reduced quality of life, and increased healthcare costs. The European Respiratory Society and European Society of Intensive Care Medicine have suggested a hierarchy of ICU mobilization to combat these issues. Weaning from mechanical ventilators as early as possible is crucial to avoid further complications. This study introduces a Targeted Mobility Therapy (TMT), a novel strategy that includes inspiratory muscle strength training, bronchial hygiene, and active mobilization, aiming to improve weaning success, reduce days on mechanical ventilators, shorten hospital stays, and enhance functional mobility. During the study, the mechanical ventilator will measure the plateau pressure (maximal inspiratory pressure) to assess inspiratory muscle strength. Spontaneous breathing trials will be conducted when the underlying cause of acute respiratory failure stabilizes or significantly improves. These trials can last from 30 minutes to 120 minutes, combined with CPAP. If a trial fails, the patient will return to full ventilatory support for at least 24 hours before a new trial is performed. Weaning success is defined as extubation and the absence of ventilatory support 48 hours following extubation.