Fluido gingival crevicular Chemerin y Factor de crecimiento de fibroblastos 21 como biomarcadores de enfermedad periodontal en pacientes diabéticos y no diabéticos

This study focuses on understanding the potential role of two substances, Chemerin and Fibroblast Growth Factor 21 (FGF21), found in gingival crevicular fluid (GCF), a fluid present in the gums. The goal is to determine if these substances can serve as markers for periodontal disease, a common gum condition, and to explore their role in the connection between periodontitis and diabetes. The study involves three groups: diabetic patients with periodontitis, patients with only periodontitis, and healthy individuals without periodontitis or any other medical conditions. During the study, GCF samples are collected from all participants to measure the levels of Chemerin and FGF21. These samples are then analyzed using a technique called ELISA. The primary outcomes of the study include measuring the levels of FGF21 in the GCF of diabetic patients with periodontitis, in patients with only periodontitis, and in healthy individuals. This observational study aims to provide valuable insights into the potential use of these substances as biomarkers for periodontal disease and their association with diabetes.