Perioperative Gut Microbiota and Post-operative Ileus in Colorectal Cancer Patients

This study focuses on understanding postoperative ileus (POI), a common condition that can occur after abdominal surgery, particularly in patients with colorectal cancer. POI can cause symptoms such as abdominal swelling, nausea, vomiting, and difficulty passing stools, leading to extended hospital stays and increased risk of complications. The exact cause of POI is still unclear, but researchers believe that changes in gut bacteria during the surgery period may contribute to this condition. This study aims to explore how the gut microbiome of colorectal cancer patients changes during the time of surgery, and how these changes might be linked to POI. During the study, the composition of gut bacteria in colorectal cancer patients will be analyzed using advanced sequencing techniques. The study will compare changes in gut bacteria between two groups of patients. The primary outcomes of the study include understanding the diversity and structure of gut bacteria, as well as identifying specific types of bacteria that might be associated with POI. The study will also measure the time it takes for patients to have their first bowel movement after surgery, as this is an important indicator of gut recovery.