TOOLBOXCerebral Bases of Tool Use and Tool Evolution
fMRI
Estudio de Ciencia Básica
Resumen
Fecha de inicio: 14 de noviembre de 2018
Fecha en la que se inscribió al primer participante.Tool use is considered to be the hallmark of complex cognitive adaptations that humans have achieved trough evolution, that provides an adaptive advantage to the human species. Even if nonhuman species do use tools too, human tool use is much more complex and sophisticated. Besides, only humans can make their tools evolve by improving them. If Man has special abilities for tool use, it has to be grounded in a specific neuroanatomical substrate. Humans and nonhumans share a similar prehension system located within the superior parietal lobe and the intraparietal sulcus. However, there is a human specificity : the surpramarginal gyrus within the left inferior parietal lobe is unique to Man, and could play a central role in tool use and tool evolution. This project aims to study the neural correlates of human tool use with functional Magnetic Resonance Imaging (fMRI), to precise the cognitive mechanisms through which humans are able to use tools. We also wish to study what are the cognitive abilities that allow us to make our tools evolve by improving them, and the neural correlates associated.
Protocolo
Esta sección proporciona detalles del plan del estudio, incluyendo cómo está diseñado y qué se está evaluando.Se reclutarán 70 pacientes
Número total de participantes que el ensayo clínico espera reclutar.Estudio de Ciencia Básica
Elegibilidad
Los investigadores buscan pacientes que cumplan ciertos criterios, conocidos como criterios de elegibilidad: estado general de salud o tratamientos previos.Cualquier sexo
Sexo biológico de los participantes elegibles para inscribirse.De 18 a 65 años
Rango de edades de los participantes que pueden unirse al estudio.Voluntarios sanos permitidos
Indica si personas sanas, sin la condición que se estudia, pueden participar.Criterios
Inclusion Criteria: * To be between the ages of 18 and 65 years old * Having given an informed consent for the study * Being right-handed * Being registered with the French Social Security System Exclusion Criteria: * No signature on the consent form, including inability to read or write French. * Neurologic or psychiatric illness, known or revealed durnig the inclusion visit * Substance intake ( taking psychoactive medications or recreational drugs) on the day of the experiment * Noise intolerance * Minor person, pregnant or breastfeeding woman * Persons under curatorship or deprived of civil rights or deprived of their freedom * Unable to fill a questionnaire (severe cognitive troubles) * Subjects must not have metallic or electronic implants in the body : pacemakers or pacemaker wires, open heart surgery, artificial heart valve, brain aneurysm surgery, middle ear implant, hearing aid, braces or extensive dental work, cataract surgery or lens implant, implanted mechanical or electrical device, or artificial limb or joint o foreign metallic objects in the body (bullets, BBs, pellets, schrapnel, or metalwork fragments) or current or past employment as machinists, welders or metal workers, tattoos near the head or neck regions, permanent makeup * Claustrophobia
Plan de Estudio
Conoce todos los tratamientos administrados en este estudio, su descripción detallada y en qué consisten.2 grupos de intervención están designados en este estudio
0% de probabilidad de ser asignado al grupo placebo
Grupos de Tratamiento
Grupo I
Grupo II
Objetivos del Estudio
Objetivos Primarios
Objetivos Secundarios
Centros del Estudio
Estos son los hospitales, clínicas o centros de investigación donde se lleva a cabo el estudio. Puedes encontrar la ubicación más cercana a ti y su estado de reclutamiento.Este estudio tiene una ubicación
Laboratoire d'Etude des Mécanismes Cognitifs (EMC) -Université Lumière Lyon 2
Lyon, FranceAbrir Laboratoire d'Etude des Mécanismes Cognitifs (EMC) -Université Lumière Lyon 2 en Google Maps