Investigation of the Arterial Effects of the Veinoplus(r) Stimlator Device.

Investigations are conducted in an air-conditioned 22+/-2 °C room, with the patient comfortably seated on an armchair. Measured ware started at rest and performed throughout the period pf stimulation and for 10 minutes after the end of the stimulation Muscle stimulation: We apply a series of 20 minutes of stimulation with the Veinoplus® device. The device delivers a stimulation of incremental rate with 5 minutes intervals, with 1 Hz, 1.25 Hz, 1.5 Hz and 1.75 Hz and then stops automatically. Ultrasound measurements The Diameter of the superficial femoral artery was measured at rest on both sides before each study. The VTI of 3 cardiac cycles (three peaks systolic velocity) will be measured by duplex ultrasound imaging, to calculate the arterial inflow to the leg. Results will be expressed in l /min. Tcpo2 recording TcpO2 is measured at the chest and on both calves with TCM 400 (Radiometer, DK). Results are expressed in DROP index(mmHg) values. Near Infra-red spectroscopy (NIRS) We use the ARTinis NIRS device (ARTinis; NL) to estimate tissue saturation (StO2) on both gastrocnemius muscles of the leg. Systemic hemodynamic parameters Systemic and diastolic arterial pressures and heart rate are recorded every two minutes using Dinamap V100 (GE france).