Project Inspire: A New Translational Tool for Studying the Role of Breathing in Meditation
Mindful Breathing (MB) Intervention
+ Usual Care (UC) Control Condition
Enfermedades Cardiovasculares+4
+ Hipertensión
+ Procesos Patológicos
Estudio de Prevención
Resumen
Fecha de inicio: 1 de febrero de 2011
Fecha en la que se inscribió al primer participante.A recent National Health Interview Survey reported that breathing exercises were the second most common complementary and alternative medicine practice in the United States, following only the use of "natural products." With such widespread interest in breathing exercises, alone or as a component of practices such as meditation, a need exists for research that examines not only its efficacy, but also investigates potential mechanisms of action. Indeed, a recent National Center for Complementary and Alternative Medicine (NCCAM) Meditation Workshop recommended research to clarify biological pathways by which meditation practices, including breathing exercises, can impact health. To explore mechanisms underlying the health effects of breathing exercises, new translational tools are needed that can measure breathing patterns in both the clinic and natural environment. The primary objective of the present proposal is the application of a new technology to the investigation of pathways by which breathing exercises can affect health. For this project, the health-related outcome measure to be studied is a major cardiovascular risk factor, blood pressure.
Protocolo
Esta sección proporciona detalles del plan del estudio, incluyendo cómo está diseñado y qué se está evaluando.Se reclutarán 99 pacientes
Número total de participantes que el ensayo clínico espera reclutar.Estudio de Prevención
Elegibilidad
Los investigadores buscan pacientes que cumplan ciertos criterios, conocidos como criterios de elegibilidad: estado general de salud o tratamientos previos.Mujer
Sexo biológico de los participantes elegibles para inscribirse.A partir de 50 años
Rango de edades de los participantes que pueden unirse al estudio.Voluntarios sanos no permitidos
Indica si personas sanas, sin la condición que se estudia, pueden participar.Condiciones
Patología
Criterios
Inclusion Criteria * Mean 24-hr SBP: 130-139 mmHg * Female * \> 50 years of age * Post menopausal, defined as greater than or equal to one year without a menstrual cycle. * Body Mass Index (BMI): 19-31 * English speaking (Patients not able to read and speak English will be excluded as the behavioral group interventions are conducted in English) * Has a personal physician Exclusion Criteria (Individuals will be filtered in the KP OSCA database according to the following ICD-9 codes): Respiration: * 491.X chronic Bronchitis incl COPD * 492.X emphysema * 493.X asthma * 494-496; 500-519: all kinds of chronic pulmonary conditions Cardiovascular: * 404.9 chronic ischemic heart disease * 425.X cardiomyopathies * 428.X heart failure * 430-438 cerebrovascular diseases Kidney: * 582-583 chronic glomerulonephritis * 584-588 renal failure Liver: \- 571.X chronic liver disease and cirrhosis Smoker: 305.1 Psychiatric: * 290-299 dementia/schizophrenia/ psychoses… * 303, 304 alcohol or drug dependence * 317-319 mental retardation Medications: * All blood pressure medications * All tranquilizers, benzodiazepins if prescribed regularly, e.g. every month * All narcotics if prescribed regularly, e.g. every month Other: \- Plan to relocate residence outside recruitment area during the intervention or follow- period
Plan de Estudio
Conoce todos los tratamientos administrados en este estudio, su descripción detallada y en qué consisten.2 grupos de intervención están designados en este estudio
0% de probabilidad de ser asignado al grupo placebo
Grupos de Tratamiento
Grupo I
ExperimentalGrupo II
Objetivos del Estudio
Objetivos Primarios
Objetivos Secundarios