Heparin-Coated Intraocular Lens for Uveitis Patients After Cataract Surgery
Colección de datos
Catarata+2
+ Enfermedades Oculares
+ Enfermedades del Cristalino
Estudio de Tratamiento
Resumen
Fecha de inicio: 1 de marzo de 1994
Fecha en la que se inscribió al primer participante.This study focuses on patients with uveitis, a condition that can lead to complications after cataract surgery with intraocular lens implantation. These complications may include iris adhesions to the lens, cellular deposits on the lens surface obscuring vision, and uveitis itself. The study aims to investigate the safety and effectiveness of a heparin-coated intraocular lens, which may offer a more compatible surface and potentially reduce post-surgery complications. This research is crucial as it could pave the way for improved care and reduced risks for uveitis patients undergoing cataract surgery. In this study, 80 patients with a history of uveitis who require cataract surgery will be randomly assigned to receive either a heparin-coated intraocular lens or an unmodified lens. The primary goal is to evaluate the development of cellular deposits on the lens surface one year after surgery. These deposits will be assessed using standard photographs by a masked grader. Secondary goals include measuring visual acuity, intraocular inflammation, the development of anterior and posterior synechiae, and corneal endothelial cell counts.
Protocolo
Esta sección proporciona detalles del plan del estudio, incluyendo cómo está diseñado y qué se está evaluando.Estudio de Tratamiento
Elegibilidad
Los investigadores buscan pacientes que cumplan ciertos criterios, conocidos como criterios de elegibilidad: estado general de salud o tratamientos previos.Cualquier sexo
Sexo biológico de los participantes elegibles para inscribirse.A partir de 18 años
Rango de edades de los participantes que pueden unirse al estudio.Condiciones
Patología
Criterios
Women and men 18 years or older with a documented history of uveitis in an eye requiring cataract surgery are eligible for the study. In all patients, the eye must be free of active inflammation for at least 3 months before surgery, with or without anti-inflammatory medications. Exclusion criteria include corneal pathology or hazy media that preclude evaluation of the intraocular lens, uncontrolled glaucoma, and diabetes mellitus. Monocular patients and patients who cannot be followed for at least 1 year are also excluded.
Centros del Estudio
Estos son los hospitales, clínicas o centros de investigación donde se lleva a cabo el estudio. Puedes encontrar la ubicación más cercana a ti y su estado de reclutamiento.Este estudio tiene una ubicación
National Institutes of Health
Bethesda, United StatesAbrir National Institutes of Health en Google Maps