[18F]-Fluoromannitol PET Contrast Agent in Healthy Volunteers

This study focuses on understanding how a special imaging agent called 18F-Fluoromannitol (18F-FMtl) behaves in the body and checking its safety. This agent is used in a type of scan called a PET scan, which helps doctors see inside the body. The study involves healthy adult volunteers and is important because 18F-FMtl is not yet available for general use and hasn’t been tested in humans before. By evaluating how this agent moves through the body, researchers aim to gather important safety information, which could potentially lead to better diagnostic tools in the future. Participants in this study will receive 18F-FMtl through an intravenous injection, meaning it is administered directly into the bloodstream. Following this, PET scans will be conducted to track the agent’s movement and accumulation in the body. Additionally, researchers will collect blood and urine samples, monitor vital signs, and check for any symptoms to ensure safety. The study is carefully designed to evaluate these factors, providing a comprehensive understanding of the agent's behavior and safety profile.