Effects of Multidisciplinary Interventions in Elderly Asthma Patients With Risk of Acute Exacerbation
Magnesium
+ Education for asthma action plan
+ hot-lines for acute exacerbation of asthma
Bronchial Diseases+11
+ Deficiency Diseases
+ Hypersensitivity
Prevention Study
Summary
Study start date: June 1, 2012
Actual date on which the first participant was enrolled.We want to examine the effect of multidisciplinary interventions in asthma patients who had experienced acute exacerbation of asthma. In our previous observational studies, elderly asthma patients had a some distinct features such as impairment of cognitive function, deficiency of micronutrient and absence of caregiver compared with young adult asthmatics. We wanted to evaluate whether the long-term course of asthma could be modified by intervening deficienies which were found in elderly patiensts. So, we designed a interventional study to correct above risk factors in elderly asthma patients, which could be aggravating their asthma. Followings are our specific multidiciplinary items that we want to correct. popularize and educate the asthma action plan run a emergency call system for acute exacerbation educate the proper techniques using inhalers correct the deficiency of magnesium (magnesium 500 mg per day) After 1 years, we will measure the numbers of acute exacerbations, lung function including FEV1 and FEV1/FVC, health-related quality of life and level of serum magnesium in study patients.
Protocol
This section provides details of the study plan, including how the study is designed and what the study is measuring.360 patients to be enrolled
Total number of participants that the clinical trial aims to recruit.Prevention Study
Eligibility
Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.Any sex
Biological sex of participants that are eligible to enroll.Over 65 Years
Range of ages for which participants are eligible to join.Healthy volunteers not allowed
If individuals who are healthy and do not have the condition being studied can participate.Conditions
Pathology
Criteria
Inclusion Criteria: elderly asthma patients who had experienced acute exacerbation of asthma 1)aggravations of any of major criteria dyspnea cough wheezing increase or purulent changes of sputum nocturnal symptoms 2)aggravation of more than one of following criteria a reduction of forced expiratory volume at one second or peak expiratory flow rate more than 20% compared than one's best score unscheduled clinic or emergency department visit or admission step-up of dose of asthma medications or any intake of systemic steroids
Study Plan
Find out more about all the medication administered in this study, their detailed description and what they involve.One single intervention group is designated in this study
This study does not include a placebo group
Treatment Groups
Group I
ExperimentalStudy Objectives
Primary Objectives
Secondary Objectives
Study Centers
These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.This study has 1 location
Seoul National University Hospital
Seoul, South KoreaOpen Seoul National University Hospital in Google Maps