Completed

The Effect of the Glycemic Load of Meals on the Cognition and Mood of Older Adults With Differences in Glucose Tolerance

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What is being tested

Isomaltulose

+ Sucrose

+ Glucose

Dietary Supplement
Who is being recruted

Mental Disorders+3

+ Brain Diseases

+ Central Nervous System Diseases

From 45 to 80 Years
+5 Eligibility Criteria
See all eligibility criteria
How is the trial designed

Basic Science Study

Interventional
Study Start: September 2011
See protocol details

Summary

Principal SponsorSwansea University
Last updated: December 11, 2014
Sourced from a government-validated database.Claim as a partner

Study start date: September 1, 2011

Actual date on which the first participant was enrolled.

On day one subjects will take an oral glucose tolerance test and will then be divided into four groups depending on their glucose tolerance (how long values remain raised) and the tendency for values to subsequently fall to low values. On a second occasion 155 healthy older adults, aged 45-80 years, will be randomly assigned to receive either a glucose, sucrose or isomaltulose based meal. All meals are matched on macronutrient composition and differ only in glycemic load. Cognitive performance and mood will be assessed 30, 105 and 180 minutes after breakfast. Measures of memory, attention, reaction times and mood will be taken. The response to the three meals will be contrasted in those with different glucose profiles on day one

NCT01842022
Principal SponsorSwansea University
Last updated: December 11, 2014
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.
Design Details

155 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.

Basic Science Study

Basic science studies help researchers understand how the body works or how a disease develops. They don't test treatments, but they build the foundation for future therapies.

Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Conditions
Criteria

Any sex

Biological sex of participants that are eligible to enroll.

From 45 to 80 Years

Range of ages for which participants are eligible to join.

Healthy volunteers allowed

If individuals who are healthy and do not have the condition being studied can participate.

Conditions

Pathology

Mental DisordersBrain DiseasesCentral Nervous System DiseasesNervous System DiseasesNeurocognitive DisordersDementia

Criteria

1 inclusion criteria required to participate
Healthy adults of 45 to 80 years
4 exclusion criteria prevent from participating
Dementia
Gastro-intestinal problems
Liver disease
Type 1 or type 2 diabetes

Study Plan

Find out more about all the medication administered in this study, their detailed description and what they involve.
Treatment Groups
Study Objectives

4 intervention groups are designated in this study

This study does not include a placebo group 

Treatment Groups

Group I

Take meals with isomaltulose, sucrose or glucose

Group II

Take meals with isomaltulose, sucrose or glucose

Group III

Take meals with isomaltulose, sucrose or glucose

Group IV

Take meals with isomaltulose, sucrose or glucose

Study Objectives

Primary Objectives

Secondary Objectives

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 1 location

Psychology, Swansea University

Swansea, United KingdomOpen Psychology, Swansea University in Google Maps
CompletedOne Study Center