Understanding Disparities in Quitting in African American and White Smokers

Study start date: February 1, 2013

Inclusion Criteria: Non-Hispanic African American or non-Hispanic White ≥ 18 years of age Smoked 3-20 cigarettes per day Smoked on >25 days of the past 30 days Functioning telephone Interested in quitting smoking Interested in taking 3 months of varenicline Willing to complete all study visits Exclusion Criteria: Renal impairment Evidence or history of clinically significant allergic reactions to varenicline A cardiovascular event in the past month Hospitalization in the past 2 months for any cardiovascular disease, including but not limited to: Angina Myocardial infarction Peripheral vascular disease Stroke New onset of chest pain or arrhythmia in the past 2 months History of alcohol or drug dependency in the past year Major depressive disorder in the last year requiring treatment History of panic disorder, psychosis, bipolar disorder, or eating disorders Use of tobacco products other than cigarettes in past 30 days Use of pharmacotherapy in the month prior to enrollment, including prior use of varenicline Pregnant, contemplating getting pregnant, or breastfeeding Plans to move from Kansas City during the treatment and follow-up phase Another household member enrolled in the study