Dismantling Mindfulness: Contributions of Attention vs. Acceptance
Focused Attention (FA)
+ Open- Monitoring
+ Mindfulness-Based Cognitive Therapy
Treatment Study
Summary
Study start date: February 1, 2013
Actual date on which the first participant was enrolled.Meditation, particularly mindfulness meditation, is one of the most popular Complementary and Alternative Medicine (CAM) therapies for alleviating emotional stress, depression and anxiety. While standardized meditation-based treatment packages like Mindfulness Based Stress Reduction (MBSR) and Mindfulness-based Cognitive Therapy (MBCT) have reliably shown sustained improvements in emotional disturbances and wellbeing, they contain so many different components and practices that the active ingredient cannot be ascertained. What is commonly called "Mindfulness" meditation is actually comprised of two separate practices: 1) focused awareness practice (FA), and 2) open-monitoring practice (OM). This project aims to create separate 8 week programs for FA and OM meditations, compare their clinical efficacy and investigate their separate mechanisms of action in individuals with clinically significant levels of persistent negative affect and depression. The clinical benefit and mechanism of action of focused awareness (FA) vs open-monitoring (OM) vs MBCT will be examined with a 3-armed randomized control trial of these 8 week interventions. Outcome variables include negative affect (depression, anxiety, stress) and wellbeing. Hypothesized mediating processes include objectively measured attention, emotion regulation and the basic wakefulness on which they depend.
Protocol
This section provides details of the study plan, including how the study is designed and what the study is measuring.104 patients to be enrolled
Total number of participants that the clinical trial aims to recruit.Treatment Study
Eligibility
Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.Any sex
Biological sex of participants that are eligible to enroll.From 18 to 65 Years
Range of ages for which participants are eligible to join.Healthy volunteers not allowed
If individuals who are healthy and do not have the condition being studied can participate.Criteria
Inclusion Criteria: English-speaking ages 18-65 mild-severe levels of depression or high level of negative affect Exclusion Criteria: Current: age <18 or >65 inability to read and write in English Extremely severe levels of depression active suicidal ideation presence of Axis I personality disorder panic disorder post-traumatic stress disorder obsessive-compulsive disorder eating disorder, or substance abuse/dependence current psychotherapy change in antidepressant medication type or dosage in the last 8 weeks. Lifetime history exclusions: bipolar disorder psychotic disorders persistent antisocial behavior or repeated self-harm, borderline personality disorder, organic brain damage regular meditation practice
Study Plan
Find out more about all the medication administered in this study, their detailed description and what they involve.3 intervention groups are designated in this study
This study does not include a placebo group
Treatment Groups
Group I
ExperimentalGroup II
ExperimentalGroup III
ExperimentalStudy Objectives
Primary Objectives
Secondary Objectives
Study Centers
These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.This study has 1 location
Brown University Clinical and Affective Neuroscience Laboratory
Providence, United StatesOpen Brown University Clinical and Affective Neuroscience Laboratory in Google Maps