Completed

Effects of Sleep Deprivation on Metabolism and Cognition

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Study Aim

This study aims to investigate how partial sleep deprivation affects your procedural and spatial memory performance, by comparing results after a normal night's sleep and after a night of partial sleep deprivation.

What is being tested

Ideal Food Portion Selection

+ Morning Blood Test After Sleep Change

+ 30-minute Interference Task

BehavioralProcedure
Who is being recruted

Mental Disorders+5

+ Nervous System Diseases

+ Neurologic Manifestations

From 20 to 28 Years
+13 Eligibility Criteria
See all eligibility criteria
How is the trial designed

Basic Science Study

Interventional
Study Start: April 2013
See protocol details

Summary

Principal SponsorUppsala University
Last updated: August 12, 2026
Sourced from a government-validated database.Claim as a partner

Study start date: April 1, 2013

Actual date on which the first participant was enrolled.

It is predicted that partial sleep deprivation negatively affects the hormonal status, e.g. upregulating ghrelin and other hunger-promoting hunger hormones, while showing impaired memory functions. It is also predicted that participants will tend to increase their desired portion sizes after partial sleep deprivation, compared with after a normal night's sleep.

NCT01823263
Principal SponsorUppsala University
Last updated: August 12, 2026
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.
Design Details

18 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.

Basic Science Study

Basic science studies help researchers understand how the body works or how a disease develops. They don't test treatments, but they build the foundation for future therapies.

Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Conditions
Criteria

Male

Biological sex of participants that are eligible to enroll.

From 20 to 28 Years

Range of ages for which participants are eligible to join.

Healthy volunteers allowed

If individuals who are healthy and do not have the condition being studied can participate.

Conditions

Pathology

Mental DisordersNervous System DiseasesNeurologic ManifestationsSigns and SymptomsSleep Wake DisordersPathological Conditions, Signs and SymptomsDyssomniasSleep Deprivation

Criteria

6 inclusion criteria required to participate
Age 20-28y
Healthy (self-reported) and not on medication
Male
Non-smoking
Show More Criteria
7 exclusion criteria prevent from participating
A history of endocrine, neurological or psychiatric disorders
Any dietary issues with the food items provided
Any sleep conditions (e.g. irregular bedtimes, sleep complaints)
Major illness
Show More Criteria

Study Plan

Find out more about all the medication administered in this study, their detailed description and what they involve.
Treatment Groups
Study Objectives

2 intervention groups are designated in this study

This study does not include a placebo group 

Treatment Groups

Group I

Experimental
Participants in this group have limited sleep and undergo various tasks and procedures, including memory tests, a portion size task, and blood samples.

Group II

Experimental
Participants in this group will have a full night's sleep before undergoing various tasks and tests. These include memory tasks, a working memory function task, a portion size task, and an interference task. Blood samples will also be taken.

Study Objectives

Primary Objectives

Secondary Objectives

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 1 location

Department of Neuroscience, Uppsala University

Uppsala, SwedenOpen Department of Neuroscience, Uppsala University in Google Maps
CompletedOne Study Center