Completed

Influence of Pistachios on Performance and Exercise-induced Inflammation, Oxidative Stress, and Immune Dysfunction in Athletes: a Metabolomics-based Approach.

0 criteria met from your profileSee at a glance how your profile meets each eligibility criteria.
What is being tested

Pistachios

Other
Who is being recruted

Pathologic Processes+1

+ Pathological Conditions, Signs and Symptoms

+ Immune System Diseases

From 18 to 55 Years
+10 Eligibility Criteria
See all eligibility criteria
How is the trial designed

Prevention Study

Interventional
Study Start: March 2013
See protocol details

Summary

Principal SponsorAppalachian State University
Last updated: February 2, 2015
Sourced from a government-validated database.Claim as a partner

Study start date: March 1, 2013

Actual date on which the first participant was enrolled.

Ingestion of 3 ounces of pistachio nuts per day for two weeks before and the day of cycling intensely for 75 kilometers will support substrate utilization during exercise (as determined through metabolomics) and improve performance compared to water only, and attenuate inflammation, oxidative stress, and immune dysfunction during 24 hours of recovery.

NCT01821820
Principal SponsorAppalachian State University
Last updated: February 2, 2015
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.
Design Details

40 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.

Prevention Study

Prevention studies aim to stop a disease from developing. They often involve people at risk and test things like vaccines, lifestyle changes, or preventive medications.

Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Conditions
Criteria

Male

Biological sex of participants that are eligible to enroll.

From 18 to 55 Years

Range of ages for which participants are eligible to join.

Healthy volunteers allowed

If individuals who are healthy and do not have the condition being studied can participate.

Conditions

Pathology

Pathologic ProcessesPathological Conditions, Signs and SymptomsImmune System DiseasesInflammation

Criteria

6 inclusion criteria required to participate
Ages 18-55
Agree to avoid herbs and medications that influence inflammation
Agree to avoid the use of large dose vitamin/mineral supplements
Agree to train normally and stay weight stable
Show More Criteria
4 exclusion criteria prevent from participating
At moderate or high risk for cardiovascular disease
No history of competing in cycling races
Regularly take supplements or medicines known to effect inflammation
Younger than 18 or older than 55 years of age

Study Plan

Find out more about all the medication administered in this study, their detailed description and what they involve.
Treatment Groups
Study Objectives

2 intervention groups are designated in this study

This study does not include a placebo group 

Treatment Groups

Group I

Experimental
Pistachio treatment (3 oz/d) for two weeks; 3 oz pistachio nuts and water (1.5 oz. before, and 1.5 oz during) cycling 75 km.

Group II

No Intervention
No pistachios for two weeks, or before and during 75 km cycling.

Study Objectives

Primary Objectives

Secondary Objectives

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 1 location

ASU Human Performance Laboratory, North Carolina Research Campus

Kannapolis, United StatesOpen ASU Human Performance Laboratory, North Carolina Research Campus in Google Maps
CompletedOne Study Center