Completed

SPMedicinesAvaliação in Vivo do Potencial cariogênico e Erosivo de Bebidas e Medicamentos pediátricos líquidos Intra-orais

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What is being tested

G4 and G5

+ G1, G2 and G3

Other
Who is being recruted

Stomatognathic Diseases+1

+ Tooth Diseases

+ Tooth Demineralization

From 18 to 22 Years
+9 Eligibility Criteria
See all eligibility criteria
How is the trial designed

Prevention Study

Phase 2
Interventional
Study Start: August 2011
See protocol details

Summary

Principal SponsorFederal University of Paraíba
Last updated: March 27, 2013
Sourced from a government-validated database.Claim as a partner

Study start date: August 1, 2011

Actual date on which the first participant was enrolled.

Te study was carried out with 12 subjects that were refrained from brushing their teeth for 28 h and did not eat or drink for at least 3 h prior to each appointment. Dental biofilm pH was measured in the cervical and proximal regions of anterior teeth with beetrode-type microelectrode coupled to a potentiometer. The biofilm was submitted nine paediatric medicines a long term and sucrose (negative control). pH measurements were taken at baseline to determine resting plaque pH and at time interval 5, 10, 15, 20, 25 and 30 minutes.

NCT01819350
Principal SponsorFederal University of Paraíba
Last updated: March 27, 2013
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.
Design Details

12 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.

Prevention Study

Prevention studies aim to stop a disease from developing. They often involve people at risk and test things like vaccines, lifestyle changes, or preventive medications.

Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Conditions
Criteria

Any sex

Biological sex of participants that are eligible to enroll.

From 18 to 22 Years

Range of ages for which participants are eligible to join.

Healthy volunteers allowed

If individuals who are healthy and do not have the condition being studied can participate.

Conditions

Pathology

Stomatognathic DiseasesTooth DiseasesTooth DemineralizationDental Caries

Criteria

4 inclusion criteria required to participate
Age 18 to 22 years
Having 20 natural teeth incluing molar
Having Oral hygiene adequate (OHI < 1.1)
Not havind oral disease
5 exclusion criteria prevent from participating
Biofilm baseline pH > 5,5
Having used medicines last 3 months
Not signature consent term
Pregant woman
Show More Criteria

Study Plan

Find out more about all the medication administered in this study, their detailed description and what they involve.
Treatment Groups
Study Objectives

2 intervention groups are designated in this study

This study does not include a placebo group 

Treatment Groups

Group I

Experimental
Application of antibiotic group of pediatric medicines and control group (sucrose 10 %)on dental biofilm.

Group II

Experimental
Application of Nutritional, Respiratory and Endocrine groups medicines pediatric on dental biofilm

Study Objectives

Primary Objectives

Secondary Objectives

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 1 location

Federal University of Paraíba

João Pessoa, BrazilOpen Federal University of Paraíba in Google Maps
CompletedOne Study Center