Completed

Genetic Predictors of Response to a Computerized Self-help Program for Depression

0 criteria met from your profileSee at a glance how your profile meets each eligibility criteria.
What is being tested

Computerized self-help program for depression

Behavioral
Who is being recruted

Behavior+4

+ Mental Disorders

+ Behavioral Symptoms

From 18 to 55 Years
+8 Eligibility Criteria
See all eligibility criteria
How is the trial designed

Treatment Study

Interventional
Study Start: March 2013
See protocol details

Summary

Principal SponsorUniversity of Texas at Austin
Last updated: November 9, 2015
Sourced from a government-validated database.Claim as a partner

Study start date: March 1, 2013

Actual date on which the first participant was enrolled.

The goal of this project is to determine whether genetic information can be used to predict response to an internet-based treatment of depression. Several studies now indicate that completing an internet-based treatment for depression, called Deprexis, can significantly improve symptoms of depression. However, not everyone improves. The purpose of this study is to determine whether genetic profile can predict who is likely to improve.

NCT01818453
Principal SponsorUniversity of Texas at Austin
Last updated: November 9, 2015
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.
Design Details

500 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.

Treatment Study

These studies test new ways to treat a disease, condition, or health issue. The goal is to see if a new drug, therapy, or approach works better or has fewer side effects than existing options.

Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Conditions
Criteria

Any sex

Biological sex of participants that are eligible to enroll.

From 18 to 55 Years

Range of ages for which participants are eligible to join.

Healthy volunteers not allowed

If individuals who are healthy and do not have the condition being studied can participate.

Conditions

Pathology

BehaviorMental DisordersBehavioral SymptomsDepressive DisorderDepressionDepressive Disorder, MajorMood Disorders

Criteria

5 inclusion criteria required to participate
Be stable on medication and/or therapy (i.e. no changes within 2 weeks of study entry)
Be willing to donate saliva for DNA research
English-speaking
Have a current symptoms of depression
Show More Criteria
3 exclusion criteria prevent from participating
Any diagnosis of a psychotic or bipolar disorder
Having current suicidal risk warranting crisis intervention
Meeting for alcohol/drug dependence in the past year

Study Plan

Find out more about all the medication administered in this study, their detailed description and what they involve.
Treatment Groups
Study Objectives

2 intervention groups are designated in this study

This study does not include a placebo group 

Treatment Groups

Group I

Active Comparator
Participants will have access to a computerized self-help program for depression, called deprexis, for 8 weeks.

Group II

No Intervention
Participants randomly assigned to a "wait list control" condition will wait 8 weeks after assignment before they can access the deprexis program.

Study Objectives

Primary Objectives

Secondary Objectives

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 1 location

The University of Texas at Austin

Austin, United StatesOpen The University of Texas at Austin in Google Maps
CompletedOne Study Center