Completed

A Prospective, Randomized, Double Blind With Sham Control, Clinical Study to Assess the Safety and Efficacy of Low Intensity Extracorporeal Shockwave Therapy (LI-ESWT) by 'Renova' in Patients With Erectile Dysfunction

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What is being tested

Shockwave system

+ Sham treatment

Device
Who is being recruted

Urogenital Diseases+5

+ Genital Diseases

+ Mental Disorders

From 20 to 80 Years
+15 Eligibility Criteria
See all eligibility criteria
How is the trial designed

Treatment Study

Placebo-Controlled
Interventional
Study Start: December 2012
See protocol details

Summary

Principal SponsorInitia
Last updated: May 12, 2015
Sourced from a government-validated database.Claim as a partner

Study start date: December 1, 2012

Actual date on which the first participant was enrolled.

This is a prospective, randomized, double-blind clinical study comparing safety and efficacy of the treatments performed with Renova (LI-ESWT) on symptomatic ED patients to the safety and efficacy of the control sham patients. Patients are randomized in a 1:1 ratio of Renova to the sham control group.

Principal SponsorInitia
Last updated: May 12, 2015
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.
Design Details

60 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.

Treatment Study

These studies test new ways to treat a disease, condition, or health issue. The goal is to see if a new drug, therapy, or approach works better or has fewer side effects than existing options.



Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Conditions
Criteria

Male

Biological sex of participants that are eligible to enroll.

From 20 to 80 Years

Range of ages for which participants are eligible to join.

Healthy volunteers not allowed

If individuals who are healthy and do not have the condition being studied can participate.

Conditions

Pathology

Urogenital DiseasesGenital DiseasesMental DisordersGenital Diseases, MaleSexual Dysfunction, PhysiologicalSexual Dysfunctions, PsychologicalMale Urogenital DiseasesErectile Dysfunction

Criteria

6 inclusion criteria required to participate
Good general health

International Index of Erectile Function 6 (IIEF-EF) between 11 to 25

Negative response to PDE5-I (unable to penetrate on demand even with maximum PDE5-I dosage,Non-responders)

Positive response to PDE5-I (able to penetrate on demand, Responders)

Show More Criteria

9 exclusion criteria prevent from participating
Anti-androgens, oral or injectable androgens

Any unstable medical, psychiatric, spinal cord injury and penile anatomical abnormalities

Clinically significant chronic hematological disease

Hormonal pathology

Show More Criteria

Study Plan

Find out more about all the medication administered in this study, their detailed description and what they involve.
Treatment Groups
Study Objectives

2 intervention groups are designated in this study

50% chance of being blinded to the placebo group

Treatment Groups

Group I

Experimental
4 weekly sessions of low-intensity shockwave therapy

Group II

Sham

Study Objectives

Primary Objectives

Secondary Objectives

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 1 location

Meir Medical Center

Kfar Saba, IsraelOpen Meir Medical Center in Google Maps
CompletedOne Study Center