Completed

The Measurement of Spine Dynamics During Gait for the Quantification of Intervention Outcomes in Patients With Different Pathologies

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What is being tested

Shoe insole

+ Modified shoe with sole lift

+ Ankle foot orthosis

Other
Who is being recruted

Bone Diseases+8

+ Bone Diseases, Developmental

+ Brain Damage, Chronic

From 10 to 18 Years
See all eligibility criteria
How is the trial designed

Treatment Study

Interventional
Study Start: July 2013
See protocol details

Summary

Principal SponsorUniversity Children's Hospital Basel
Last updated: August 28, 2018
Sourced from a government-validated database.Claim as a partner

Study start date: July 1, 2013

Actual date on which the first participant was enrolled.

Measuring spine dynamics is a necessity in order to better understand gait deviations throughout the whole body and to evaluate treatment effects on spinal movement during gait. However, the full body marker sets that are typically used in opto-electronic 3D gait analyses either disregard the spine entirely or regard it as a rigid structure. Therefore, the purpose of this study is to use an enhanced trunk marker set in order to evaluate the biomechanical effects of lower extremity treatments on spine dynamics in patients with different pathologies. It has been hypothesized that the enhanced trunk marker set is a reliable method for the measurement of spine dynamics during gait in patients with deviations occurring secondary to leg length inequality. the enhanced trunk marker set is a reliable method for the measurement of spine dynamics during gait in patients that present both primary and secondary deviations such as seen in hemiplegic and diplegic cerebral palsy. treatment by means of either a shoe insole or a modified shoe with sole lift on the shorter side has an effect on spine dynamics during gait in patients with leg length inequality. treatment by means of an ankle foot orthosis to control the foot position has an effect on spine dynamics during gait in patients with hemiplegic and diplegic cerebral palsy. To verify the hypotheses, instrumented gait analyses with a standard full body marker set and the enhanced trunk marker set will be carried out before and immediately after an orthotic lower extremity treatment in the respective patient group.

Principal SponsorUniversity Children's Hospital Basel
Last updated: August 28, 2018
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.
Design Details

20 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.

Treatment Study

These studies test new ways to treat a disease, condition, or health issue. The goal is to see if a new drug, therapy, or approach works better or has fewer side effects than existing options.



Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Conditions
Criteria

Any sex

Biological sex of participants that are eligible to enroll.

From 10 to 18 Years

Range of ages for which participants are eligible to join.

Healthy volunteers not allowed

If individuals who are healthy and do not have the condition being studied can participate.

Conditions

Pathology

Bone DiseasesBone Diseases, DevelopmentalBrain Damage, ChronicBrain DiseasesCentral Nervous System DiseasesMusculoskeletal DiseasesNervous System DiseasesPathological Conditions, Signs and SymptomsPathological Conditions, AnatomicalCerebral PalsyLeg Length Inequality

Criteria

Leg length inequality patients: Inclusion Criteria: Diagnosed structural leg length inequality (minimum 1% of body height) Several different aetiologies (except neurological) Able to walk a distance of minimum 50 meters without any assistive device Exclusion Criteria: Leg length inequality due to neurological aetiology Structural deformities of the spine Obesity (> 95th BMI-per-age percentile) Injuries of the locomotor system which led to persistent deformities Hemiplegic cerebral palsy patients: Inclusion Criteria: Diagnosed hemiplegic cerebral palsy (Gross Motor Function Classification System for Cerebral Palsy (GMFCS): Levels I and II) Able to walk a distance of minimum 50 meters barefoot and without any assistive device Exclusion Criteria: Structural deformities of the spine Any previous surgical and casting treatments as well as botulinumtoxin treatments within preceding 6 months. Obesity (> 95th BMI-per-age percentile) Injuries of the locomotor system which led to persistent deformities Diplegic cerebral palsy patients: Inclusion Criteria: Diagnosed diplegic cerebral palsy (Gross Motor Function Classification System for Cerebral Palsy (GMFCS): Levels I and II) Able to walk a distance of minimum 50 meters barefoot and without any assistive device Exclusion Criteria: Structural deformities of the spine Any previous surgical and casting treatments as well as botulinumtoxin treatments within preceding 6 months. Obesity (> 95th BMI-per-age percentile) Injuries of the locomotor system which led to persistent deformities

Study Plan

Find out more about all the medication administered in this study, their detailed description and what they involve.
Treatment Groups
Study Objectives

4 intervention groups are designated in this study

This study does not include a placebo group 

Treatment Groups

Group I

Experimental
The shorter leg in a sample of 15 patients with structural leg length inequality will be corrected by either a shoe insole or a modified shoe with sole lift.

Group II

Experimental
The foot position in in a sample of 15 patients with hemiplegic cerebral palsy will be controlled by an ankle foot orthosis.

Group III

Experimental
The foot position in in a sample of 15 patients with diplegic cerebral palsy will be controlled by an ankle foot orthosis.

Group IV

No Intervention
A sample of 15 healthy controls from a simultaneously conducted study (UKBB-Spine-1315-1) will be used for comparative purposes.

Study Objectives

Primary Objectives

Secondary Objectives

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 1 location

University Children's Hospital Basel

Basel, SwitzerlandOpen University Children's Hospital Basel in Google Maps
CompletedOne Study Center