Completed

Role of Proteomics and Metallomics in Cerebral Vasospasm Following Subarachnoid Hemorrhage

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What is being collected

Data Collection

Collected from today forward - Prospective
DNA Samples
Who is being recruted

Brain Diseases+10

+ Cardiovascular Diseases

+ Central Nervous System Diseases

From 18 to 89 Years
+7 Eligibility Criteria
See all eligibility criteria
How is the trial designed

Case-Control

Comparing exposures between individuals with and without disease in order to identify potential risk factors.
Observational
Study Start: April 2011
See protocol details

Summary

Principal SponsorState University of New York - Upstate Medical University
Last updated: November 20, 2014
Sourced from a government-validated database.Claim as a partner

Study start date: April 1, 2011

Actual date on which the first participant was enrolled.

The purpose of this study is to determine the role of Proteomics and Metallomics in Cerebral Vasospasm following Subarachnoid Hemorrhage

Principal SponsorState University of New York - Upstate Medical University
Last updated: November 20, 2014
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.
Design Details

40 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.

Case-Control

These studies compare people who have a disease (cases) with those who don't (controls). The goal is to look back at previous exposures or risk factors to identify what might have contributed to the disease.


Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Conditions
Criteria

Any sex

Biological sex of participants that are eligible to enroll.

From 18 to 89 Years

Range of ages for which participants are eligible to join.

Healthy volunteers not allowed

If individuals who are healthy and do not have the condition being studied can participate.

Conditions

Pathology

Brain DiseasesCardiovascular DiseasesCentral Nervous System DiseasesCerebrovascular DisordersHemorrhageNervous System DiseasesPathologic ProcessesPathological Conditions, Signs and SymptomsVascular DiseasesIntracranial HemorrhagesHydrocephalusSubarachnoid HemorrhageVasospasm, Intracranial

Criteria

4 inclusion criteria required to participate
Control (non - hemorrhagic) group - CSF collected from patients with posterior fossa tumor or stroke with EVD in place for the management of hydrocephalus

Non traumatic SAH documented by CT scan

Patient with SAH who would need external ventricular drain (EVD) for the management of hydrocephalus

Patients with normal pressure Hydrocephalus that require an external drain

3 exclusion criteria prevent from participating
Age > 89 years or < 18 years

Recent infection within last 1 month of presentation- can increase inflammatory markers

Recent surgery or acute myocardial infarction within last 1 month of presentation

Study Plan

Find out more about all the medication administered in this study, their detailed description and what they involve.
Treatment Groups
Study Objectives

2 intervention groups are designated in this study

This study does not include a placebo group 

Treatment Groups

Study Objectives

Primary Objectives

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 1 location

State University of New York Upstate Medical University

Syracuse, United StatesOpen State University of New York Upstate Medical University in Google Maps
CompletedOne Study Center