FIDNLIntestinal Lipogenesis and Exogenous Lipid Absorption in Healthy and Obese Subjects Before and After Gastroplasty: Impact of Glucose and Fructose

This study aims to understand how the intestine processes fats in healthy individuals and obese subjects, including those who have undergone gastroplasty, a type of weight-loss surgery. The study is particularly interested in how the intestine produces new fats from sugars like glucose and fructose. This research could help improve our understanding of how obesity and weight-loss surgery affect the body's fat processing, potentially leading to better care for these conditions. Participants will consume test meals containing different combinations of cream, whey protein, fructose, and glucose. Some meals also include special forms of fructose or palmitic acid that can be traced in the body. After the meal, the study will measure how much new fat the intestine has produced and how quickly the body absorbs fats from the meal. This is done by looking for specific substances in the blood. The study has two parts, each focusing on different aspects of fat processing.