Completed

ODISNeural Correlates of the Empathogenic and Affiliative Actions of Oxytocin

0 criteria met from your profileSee at a glance how your profile meets each eligibility criteria.
What is being tested

Oxytocin

+ Placebo

Drug
Who is being recruted

From 18 to 60 Years
+6 Eligibility Criteria
See all eligibility criteria
How is the trial designed

Basic Science Study

Placebo-ControlledEarly Phase 1
Interventional
Study Start: August 2012
See protocol details

Summary

Principal SponsorUniversity Hospital, Bonn
Last updated: December 3, 2014
Sourced from a government-validated database.Claim as a partner

Study start date: August 1, 2012

Actual date on which the first participant was enrolled.

Mounting evidence indicates that the intranasal administration of the neuropeptide oxytocin has prosocial effects. However, the neural substrates of these effects are still unclear. The investigators hypothesized that a single dose administration of oxytocin should increase empathogenic and affiliative responses and that these effects are mediated by an increased insula activity.

NCT01701180
Principal SponsorUniversity Hospital, Bonn
Last updated: December 3, 2014
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.
Design Details

23 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.

Basic Science Study

Basic science studies help researchers understand how the body works or how a disease develops. They don't test treatments, but they build the foundation for future therapies.

Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Criteria

Male

Biological sex of participants that are eligible to enroll.

From 18 to 60 Years

Range of ages for which participants are eligible to join.

Healthy volunteers allowed

If individuals who are healthy and do not have the condition being studied can participate.

Criteria

2 inclusion criteria required to participate
Healthy male volunteers
In a heterosexual relationship
4 exclusion criteria prevent from participating
Current or past physical illness
Current or past psychiatric disease
Psychoactive medication
Tobacco smokers

Study Plan

Find out more about all the medication administered in this study, their detailed description and what they involve.
Treatment Groups
Study Objectives

2 intervention groups are designated in this study

50% chance of being blinded to the placebo group

Treatment Groups

Group I

Experimental
24 IU Oxytocin, intranasal application 45 min prior to the experiment

Group II

Placebo
Intranasal application, sodium chloride solution, 3 puffs per nostril

Study Objectives

Primary Objectives

Secondary Objectives

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 1 location

Department of Psychiatry, University of Bonn

Bonn, GermanyOpen Department of Psychiatry, University of Bonn in Google Maps
CompletedOne Study Center