Completed

Different Strategies Using Autoantibodies and/or CT Scan Detection of Lung Cancer

0 criteria met from your profileSee at a glance how your profile meets each eligibility criteria.
What is being tested

CT scan & Early CDT Lung test

+ CT scan & Early CDT Lung test

RadiationOther
Who is being recruted

Behavior

+ Health Behavior

+ Smoking Cessation

From 50 to 75 Years
+9 Eligibility Criteria
See all eligibility criteria
How is the trial designed

Screening Study

Interventional
Study Start: May 2012
See protocol details

Summary

Principal SponsorNational Jewish Health
Last updated: December 31, 2020
Sourced from a government-validated database.Claim as a partner

Study start date: May 1, 2012

Actual date on which the first participant was enrolled.

In this trial, the addition of a blood biomarker test is being combined with early LDCT to determine if screening with combination may result in detection of more lung cancer at an earlier stage of disease.The study will also assess if the blood test is able to detect lung cancers in high risk individuals when the LDCT is negative for cancer. There will be health-economic costs included in the final analysis of study data.

NCT01700257
Principal SponsorNational Jewish Health
Last updated: December 31, 2020
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.
Design Details

1361 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.

Screening Study

Screening studies test new methods to find diseases or risk factors early—before any symptoms appear. This helps catch health issues sooner, when they may be easier to treat.

Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Conditions
Criteria

Any sex

Biological sex of participants that are eligible to enroll.

From 50 to 75 Years

Range of ages for which participants are eligible to join.

Healthy volunteers not allowed

If individuals who are healthy and do not have the condition being studied can participate.

Conditions

Pathology

BehaviorHealth BehaviorSmoking Cessation

Criteria

3 inclusion criteria required to participate
Ages 50 - 75
At least 20 pack year history of smoking
Smokers or former smokers
6 exclusion criteria prevent from participating
A serious illness that decreases life expectancy to less than 5 years
Any current use of Oxygen
Had a CT scan of chest within last 24 months
History of any cancer within 10 yrs (except skin cancer or cervical cancer)
Show More Criteria

Study Plan

Find out more about all the medication administered in this study, their detailed description and what they involve.
Treatment Groups
Study Objectives

One single intervention group is designated in this study

This study does not include a placebo group 

Treatment Groups

Group I

Every study participant receives a CT scan & Early CDT-Lung test (biomarker blood test) for lung cancer screening purposes.

Study Objectives

Primary Objectives

Secondary Objectives

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 1 location

National Jewish Health

Denver, United StatesOpen National Jewish Health in Google Maps
CompletedOne Study Center