Confocal Analysis of Corneal Structures of Symptomatic Allergic Conjunctivitis Patients Pre and Post Treatment With Olopatadine HCL Ophthalmic Solution, 0.2%
Olopatadine hydrochloride ophthalmic solution, 0.2%
Conjunctival Diseases+4
+ Conjunctivitis
+ Eye Diseases
Summary
Study start date: September 1, 2012
Actual date on which the first participant was enrolled.Heidelberg Retina Tomograph (HRT) will be used to descriptively evaluate the corneal structures and assess the immune cell status of allergic conjunctivitis patients pre- and post-treatment with olopatadine 0.2% in relation to a normative database.
Protocol
This section provides details of the study plan, including how the study is designed and what the study is measuring.17 patients to be enrolled
Total number of participants that the clinical trial aims to recruit.Eligibility
Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.Any sex
Biological sex of participants that are eligible to enroll.Over 18 Years
Range of ages for which participants are eligible to join.Healthy volunteers not allowed
If individuals who are healthy and do not have the condition being studied can participate.Conditions
Pathology
Criteria
Inclusion Criteria: Read, sign, and date an Ethics Committee reviewed and approved informed consent form. Females of childbearing potential who: Are not breast-feeding; Do not intend to become pregnant for the duration of the study; Are using adequate birth control methods and agree to continue for the duration of the study. Able to read, understand and answer questions by investigator. Willing and able to attend all required study visits and follow directions as stipulated by the protocol and investigator. History of allergic conjunctivitis (within the past 12 months) and active signs and symptoms of ocular allergies for which treatment is necessary, in the opinion of the investigator. Visual acuity correctable to 20/30 (Snellen) or better in each eye at distance with or without glasses correction. Ocular health within normal limits as determined by the investigator. No contact lens wear 14 days prior to enrollment and willing to not wear contact lenses for the duration of the study. Willing to follow a 14-day washout period due to contraindicated medication use, if deemed necessary by investigator. Other protocol-defined inclusion criteria may apply. Exclusion Criteria: Contraindications or hypersensitivity to the use of the test article or its components. Inability or unwillingness to follow all study instructions and complete study visits as required. Only one sighted eye or visual acuity not correctable to 20/30 (Snellen) in both eyes at the Screening Visit. Ocular trauma within 6 months prior to Visit 1 in either eye. Any ocular surgical intervention within six months prior to Visit 1 or anticipation of ocular surgery during the study. Presumed or actual ocular infection within 30 days prior to Visit 1. Any severe or serious ocular condition or significant illness. Any abnormal slit-lamp findings at the time of the Screening Visit. Contact lens wear within 14 days prior to the study start and unwillingness to undergo a wash-out period of 14 days; unwilling to not wear contact lenses for the duration of the study. Use of over-the-counter (OTC) ocular medications within the past 14 days unless willing to follow wash out period. Use of topical or systemic ocular medications requiring longer than a two-week washout period. Participation in any other investigational study in the 30-day period before entry into this study (i.e., Visit 1) or concomitantly with this study. Women who are pregnant, nursing, or of childbearing potential not utilizing adequate birth control measures. Other protocol-defined exclusion criteria may apply.
Study Plan
Find out more about all the medication administered in this study, their detailed description and what they involve.One single intervention group is designated in this study
This study does not include a placebo group
Treatment Groups
Group I
ExperimentalStudy Objectives
Primary Objectives
Study Centers
These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.This study has 1 location