Completed

SYNC - YOGAYoga's Impact on Neurocardiogenic Syncope and Autonomic Dysfunction

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What is being tested

Yoga

Other
Who is being recruted

Autonomic Nervous System Diseases+9

+ Consciousness Disorders

+ Nervous System Diseases

From 18 to 60 Years
See all eligibility criteria
How is the trial designed

Treatment Study

Early Phase 1
Interventional
Study Start: June 2012
See protocol details

Summary

Principal SponsorDhanunjaya Lakkireddy, MD, FACC
Last updated: June 30, 2015
Sourced from a government-validated database.Claim as a partner

Study start date: June 1, 2012

Actual date on which the first participant was enrolled.

This study focuses on neurocardiogenic syncope (NCS), a condition that causes temporary drops in blood pressure, leading to fainting spells. It's a common issue that doctors often see in outpatient settings. Usually, patients are helped with education about syncope, managing anxiety, and developing coping skills. The study aims to explore the role of Yoga in managing this condition. Yoga is known to relieve stress and anxiety, and it has also been found to improve cardiovascular function by lowering heart rate and blood pressure. The main goal of Yoga is to gain control over the autonomic nervous system, which regulates functions like heart rate, blood pressure, and breathing rate. The researchers propose that Yoga could potentially decrease the frequency of NCS episodes and alleviate associated symptoms. Participants in this study will engage in Yoga practice. The study will measure the changes in the frequency of fainting spells before and after Yoga. It will also evaluate the differences in the occurrence of various symptoms related to NCS before and after Yoga practice. The primary goal is to see if Yoga can indeed reduce the number of fainting episodes and improve the overall condition of individuals with NCS.

Principal SponsorDhanunjaya Lakkireddy, MD, FACC
Last updated: June 30, 2015
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.
Design Details

8 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.

Treatment Study

These studies test new ways to treat a disease, condition, or health issue. The goal is to see if a new drug, therapy, or approach works better or has fewer side effects than existing options.



Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Conditions
Criteria

Any sex

Biological sex of participants that are eligible to enroll.

From 18 to 60 Years

Range of ages for which participants are eligible to join.

Healthy volunteers not allowed

If individuals who are healthy and do not have the condition being studied can participate.

Conditions

Pathology

Autonomic Nervous System DiseasesConsciousness DisordersNervous System DiseasesNeurologic ManifestationsSigns and SymptomsPathological Conditions, Signs and SymptomsSyncopeUnconsciousnessNeurobehavioral ManifestationsPrimary DysautonomiasOrthostatic IntoleranceSyncope, Vasovagal

Criteria

Inclusion Criteria: Diagnosis of recurrent Neurocardiogenic syncope At least one episode of syncope or pre-syncopal event in the last 3 months prior to enrollment Exclusion Criteria: Previously established diagnosis of any psychiatric illness. Previous history of Coronary Artery Disease, myocardial infarction, congestive heart failure, carotid sinus hypersensitivity Established diagnosis of tachy and/or brady arrhythmias, except cardioinhibiotry neurocardiogenic syncope. History of pacemaker, ICD or CRT-D implantation. Other conditions where Yoga should be avoided are: Pregnant women Subjects with untreated or uncontrolled high blood pressure Subjects with past history of Pnuemothorax. Subjects with severe cervical spondylitis and cervical, thoracic or lumbar disc prolapse. Subjects with carotid stenosis Subjects with history of psychosis (evidence of acute episodes with deep and prolonged meditation) or substance abuse. Subjects with the history of epilepsy ( evidence of acute episodes with deep and prolonged meditation) Subjects with glaucoma Subjects with history of Total Hip Replacement.

Study Plan

Find out more about all the medication administered in this study, their detailed description and what they involve.
Treatment Groups
Study Objectives

One single intervention group is designated in this study

This study does not include a placebo group 

Treatment Groups

Group I

Experimental
Participants will be asked to practice Yoga 3 times per week at a minimum, and daily at a maximum. Participants will receive training in different Yoga techniques including breathing exercises, postures and meditation. Participants will be asked to practice 1 hour Yoga sessions comprised of breathing exercises, postures and meditation.

Study Objectives

Primary Objectives

Secondary Objectives

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 1 location

University of Kansas Medical Center

Kansas City, United StatesOpen University of Kansas Medical Center in Google Maps
CompletedOne Study Center