Completed
NIRS-IVUSMultimodality Advanced Intracoronary Imaging With Near-infrared Spectroscopy and Intravascular Ultrasound to Characterize Coronary Artery Plaques Before and After Percutaneous Intervention
What is being collected
Data Collection
Collected from today forward - ProspectiveWho is being recruted
Arterial Occlusive Diseases+5
+ Arteriosclerosis
+ Cardiovascular Diseases
Over 18 Years
+8 Eligibility Criteria
How is the trial designed
Other
Utilizing specific methods not covered by standard models in order to address unique research questions.Observational
Study Start: November 2011
Summary
Principal SponsorCorewell Health West
Last updated: August 7, 2025
Sourced from a government-validated database.Claim as a partner
Study start date: November 1, 2011
Actual date on which the first participant was enrolled.This study is being performed to characterize the composition and morphologic characteristics of atherosclerotic coronary artery plaques with intra-coronary near-infrared spectroscopy and intravascular ultrasound in patients undergoing percutaneous coronary intervention.
Principal SponsorCorewell Health West
Last updated: August 7, 2025
Sourced from a government-validated database.Claim as a partner
Protocol
This section provides details of the study plan, including how the study is designed and what the study is measuring.Design Details
500 patients to be enrolled
Total number of participants that the clinical trial aims to recruit.Other
Some studies use unique or mixed approaches that don't fit standard categories. These may include innovative observational methods or studies tailored to specific research questions.
Eligibility
Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.Conditions
Criteria
Any sex
Biological sex of participants that are eligible to enroll.Over 18 Years
Range of ages for which participants are eligible to join.Healthy volunteers not allowed
If individuals who are healthy and do not have the condition being studied can participate.Conditions
Pathology
Arterial Occlusive DiseasesArteriosclerosisCardiovascular DiseasesCoronary DiseaseHeart DiseasesVascular DiseasesMyocardial IschemiaCoronary Artery Disease
Criteria
5 inclusion criteria required to participate
Coronary anatomy is deemed suitable for combined NIRS-IVUS by the interventional cardiologist performing invasive angiography and intervention
Subject is at > 18 years of age
Subject is found to have >= 1 severe coronary artery stenosis by invasive angiography and percutaneous coronary intervention is planned for definitive treatment or found to have >= 1 intermediate coronary artery stenosis and IVUS planned for lesion assessment
Subject is willing and able to provide informed written consent
Show More Criteria
3 exclusion criteria prevent from participating
Subject has coronary artery anatomy deemed by interventionalist as unsuitable for NIRS-IVUS
Subject is pregnant or suspected to be pregnant
Subject is unable to provide informed consent
Study Plan
Find out more about all the medication administered in this study, their detailed description and what they involve.Study Objectives
Study Objectives
Primary Objectives
Study Centers
These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.This study has 1 location
Spectrum Health; Frederik Meijer Heart &Vascular Institute
Grand Rapids, United StatesOpen Spectrum Health; Frederik Meijer Heart &Vascular Institute in Google MapsCompletedOne Study Center