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Serial Serum Samples Investigation for Sepsis and Postresuscitation Therapeutic Strategy

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Study Aim

This observational study aims to investigate the relationship between serial serum samples and sepsis, as well as post-resuscitation therapeutic strategies, with the primary focus on evaluating the all-cause mortality rate within one month.

What is being collected

Data Collection

Collected from today forward - Prospective
No DNA Sample
Who is being recruted

Cardiovascular Diseases+6

+ Heart Diseases

+ Infections

Over 16 Years
+7 Eligibility Criteria
See all eligibility criteria
How is the trial designed

Cohort

Tracking disease incidence in order to identify risk factors and understand disease progression over time.
Observational
Study Start: July 2006
See protocol details

Summary

Principal SponsorSeoul National University Hospital
Study ContactKyung Su Kim, MD, PhDMore contacts
Last updated: November 24, 2023
Sourced from a government-validated database.Claim as a partner

Study start date: July 1, 2006

Actual date on which the first participant was enrolled.

This study focuses on individuals who are in the emergency intensive care unit due to sepsis or postresuscitation state. The main goal is to explore their serum samples, which are the clear liquids that can be separated from clotted blood. By studying these samples, researchers aim to discover a new treatment strategy for these conditions, highlighting the importance of this research in potentially improving patient care. In this observational study, participants' serum samples are collected and studied over time. The primary outcome measured is the all-cause mortality rate within one month. This helps researchers understand the effectiveness of current treatments and identify potential areas for improvement.

Principal SponsorSeoul National University Hospital
Study ContactKyung Su Kim, MD, PhDMore contacts
Last updated: November 24, 2023
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.
Design Details

500 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.

Cohort

These studies follow a group of individuals with common characteristics (such as a condition or birth year) over a specific period to study health outcomes or exposures.


Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Conditions
Criteria

Any sex

Biological sex of participants that are eligible to enroll.

Over 16 Years

Range of ages for which participants are eligible to join.

Healthy volunteers not allowed

If individuals who are healthy and do not have the condition being studied can participate.

Conditions

Pathology

Cardiovascular DiseasesHeart DiseasesInfectionsInflammationPathologic ProcessesPathological Conditions, Signs and SymptomsSystemic Inflammatory Response SyndromeHeart ArrestSepsis

Criteria

5 inclusion criteria required to participate
Admitted to ICU

Age over 16 years old

Definition of postresuscitation status: Survived from non-traumatic cardiac arrest

Definition of sepsis: 2 or more SIRS criteria + infection is suspected

Show More Criteria

2 exclusion criteria prevent from participating
DNAR status

refusal to participate

Study Plan

Find out more about all the medication administered in this study, their detailed description and what they involve.
Treatment Groups
Study Objectives

2 intervention groups are designated in this study

This study does not include a placebo group 

Treatment Groups

Study Objectives

Primary Objectives

Secondary Objectives

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 1 location

Recruiting

Seoul National University Hospital

Seoul, South KoreaOpen Seoul National University Hospital in Google Maps
Recruiting
One Study Center