Suspended

Collection of Blood Samples for Development of Multi-disease Carrier Testing

0 criteria met from your profileSee at a glance how your profile meets each eligibility criteria.
What is being collected

Procedure Data

ProcedureDNA Samples
Who is being recruted

Central Nervous System Diseases+4

+ Nervous System Diseases

+ Neuromuscular Diseases

Over 18 Years
+7 Eligibility Criteria
See all eligibility criteria
How is the trial designed

Observational
Study Start: August 2012
See protocol details

Summary

Principal SponsorNatera, Inc.
Last updated: July 16, 2013
Sourced from a government-validated database.Claim as a partner

Study start date: August 1, 2012

Actual date on which the first participant was enrolled.

The purpose of this study is to collect blood samples to enable validation of genetic testing for diseases within a multi-disease carrier screening panel. Samples will be collected from adult women or men who have previously tested positive as carriers for various recessive conditions. These are healthy adults who carry a mutation that might place them at increased risk of having a child with a specific genetic disorder. Study participation will be open to adults that were previously tested as part of their routine medical care and where test results demonstrated positive carrier status for a specific genetic disease. Samples will be tested for the disease mutation for which the subjects provides documentation of prior testing.

Principal SponsorNatera, Inc.
Last updated: July 16, 2013
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.

Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Conditions
Criteria

Any sex

Biological sex of participants that are eligible to enroll.

Over 18 Years

Range of ages for which participants are eligible to join.

Healthy volunteers not allowed

If individuals who are healthy and do not have the condition being studied can participate.

Conditions

Pathology

Central Nervous System DiseasesNervous System DiseasesNeuromuscular DiseasesSpinal Cord DiseasesMotor Neuron DiseaseNeurodegenerative DiseasesMuscular Atrophy, Spinal

Criteria

4 inclusion criteria required to participate
18 years of age or older

Able to provide a blood sample

Individuals who are carriers of an SMN1 deletion consistent with Spinal Muscular Atrophy carrier status and are able to provide documentation of carrier status determined from prior testing

Pregnant women may be include in the study

3 exclusion criteria prevent from participating
Individuals who are not carriers of a Spinal Muscular Atrophy mutation

Individuals who are unable to provide documentation of Spinal Muscular Atrophy carrier status

Minors under the age of 18 years

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 1 location

Natera, Inc

San Carlos, United StatesOpen Natera, Inc in Google Maps
SuspendedOne Study Center