The Real Distribution of Microbiota Along the Colonic Mucosa Using a Novel Device Capable of Taking 'Protected' Biopsies
Data Collection
Collected at a single point in time - Cross-sectionalCase-Only
Examining characteristics of individuals with a disease in order to identify genetic or environmental factors contributing to the condition.Summary
Study start date: August 1, 2012
Actual date on which the first participant was enrolled.We hypothesize that the distribution of mucosal and luminal microbiota changes from proximal to distal in the colon, and by taking 'protected biopsies' there will be the opportunity to show the real distribution of microbiota according to the localisation in the colon.
Protocol
This section provides details of the study plan, including how the study is designed and what the study is measuring.10 patients to be enrolled
Total number of participants that the clinical trial aims to recruit.Case-only
Eligibility
Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.Any sex
Biological sex of participants that are eligible to enroll.Over 18 Years
Range of ages for which participants are eligible to join.Healthy volunteers not allowed
If individuals who are healthy and do not have the condition being studied can participate.Criteria
Inclusion Criteria: Ill prepared colon during index colonoscopy or sigmoidoscopy: Boston scale <3 Sufficient indication to perform colonoscopy again Exclusion Criteria: Inability to give informed consent Life expectancy < 12 months Use of combination of two platelet aggregation inhibitors Mandatory use of anti-coagulatory medication Known history of hemostatic disorder Use of systemic antibiotics in preceding 6 weeks Use of probiotic or prebiotic treatment in preceding 6 weeks Positive stool cultures for common enteric pathogens (Salmonella, Shigella, Yersinia, Campylobacter, enteropathogenic e coli) History of surgery: Resection of any part of the colon or Ileocoecal resection Presence of an ileo- or colostoma
Study Plan
Find out more about all the medication administered in this study, their detailed description and what they involve.One single intervention group is designated in this study
This study does not include a placebo group
Treatment Groups
Study Objectives
Primary Objectives
Secondary Objectives
Study Centers
These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.This study has 2 locations
Academic_Medical_Center
Amsterdam, Netherlands