Completed

Physiological and Psychosocial Correlates of Type A Behavior

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What is being collected

Data Collection

Who is being recruted

Vascular Diseases+2

+ Myocardial Ischemia

+ Cardiovascular Diseases

Until 100 Years
See all eligibility criteria
How is the trial designed

Observational
Study Start: February 1982
See protocol details

Summary

Principal SponsorNational Heart, Lung, and Blood Institute (NHLBI)
Last updated: May 13, 2016
Sourced from a government-validated database.Claim as a partner

Study start date: February 1, 1982

Actual date on which the first participant was enrolled.

BACKGROUND: The Type A behavior pattern as described by Friedman and Rosenman is characterized by extremes of competitiveness, easily aroused hostility, a sense of urgency and aggression. In 1981 the Review Panel of Coronary Prone Behavior and Coronary Heart Disease concluded that the Type A behavior pattern was associated with an increased risk for coronary heart disease. Studies have challenged the independent predictive value of the behavior pattern with respect to coronary heart disease. There was a need to develop physiological measurements related to coronary-prone behavior and to reexamine the stability of the psychological assessment. It was hypothesized that Type A behavior or some component such as hostility might be associated with a state of chronic, generalized sympathetic-adrenal arousal. Preliminary research was conducted on interpersonal dynamic correlates of Type A behavior among married couples. Research was needed on whether certain types of marriages, according to the Type A/B classification of the two spouses, are more pathogenic than others. Additional research is also needed on which components of the global Type A pattern were of primary importance as risk factors for coronary disease, and which components were enduring, which were transient, and which were situationally related. In 1982, a household survey on Type A behavior was initiated. Measures included the Jenkins Activity Survey, the Framingham Type A Questionnaire, hostility scales, and other behavioral tests. Information was also collected on demographic variables, social support, marital satisfaction, life events, social values, and job and family stress. After the household survey was completed, the respondents were contacted by the Type A interviewers and the Structured Interviews conducted. A total of 1,114 Type A interviews were completed yielding 902 primary respondents and 239 spouses. DESIGN NARRATIVE: The concurrent relationship of the Structured Interview (SI) global and component Type A behavior measures were tested to levels of chronic and acute sympathetic nervous system activity, as assessed by platelet and plasma catecholamines, heart rate, blood pressure, and pupil size. The correlations among heart rate, pupil size, blood pressure, and the plasma and platelet catecholamine measures were determined as were the relationships with reported global health, chronic disease, and functional disability levels. The five-year predictability was tested of reported global health, chronic disease, and functional disability from measures of global and component Type A behavior. Tests were made of the differences in the chronic and acute sympathetic-adrenal responses, as assessed by platelet and plasma catecholamines, pupil size, heart rate, and blood pressure, among married couples having different combinations of Structured Interview global and component Type A classifications. The five year marital stability and health of these couples were followed. A comparison was made of one week test-retest reliability with the five year stability of the Structured Interview global and component Type A measures. The study completion date listed in this record was obtained from the "End Date" entered in the Protocol Registration and Results System (PRS) record.

NCT00005155
Principal SponsorNational Heart, Lung, and Blood Institute (NHLBI)
Last updated: May 13, 2016
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.

Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Conditions
Criteria

Male

Biological sex of participants that are eligible to enroll.

Until 100 Years

Range of ages for which participants are eligible to join.

Healthy volunteers not allowed

If individuals who are healthy and do not have the condition being studied can participate.

Conditions

Pathology

Vascular DiseasesMyocardial IschemiaCardiovascular DiseasesCoronary DiseaseHeart Diseases

Criteria

No eligibility criteria

Study Centers

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CompletedNo study centers