Completed

Altered Calcium And Vitamin D Metabolism in PMDD

0 criteria met from your profileSee at a glance how your profile meets each eligibility criteria.
What is being tested

Measures of calcium and bone turnover

Procedure
Who is being recruted

Mental Disorders+5

+ Depressive Disorder

+ Menstruation Disturbances

From 18 to 45 Years
+26 Eligibility Criteria
See all eligibility criteria
How is the trial designed

Diagnostic Study

Interventional
Study Start: May 2000
See protocol details

Summary

Principal SponsorNational Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Last updated: March 2, 2010
Sourced from a government-validated database.Claim as a partner

Study start date: May 1, 2000

Actual date on which the first participant was enrolled.

Osteoporosis has become one of the most widely recognized disorders of our times affecting an estimated 25 million women in this country. Recent evidence has suggested that premenstrual syndrome (PMS) is associated with a calcium deficiency state and bone loss. This may place premenopausal women at greater risk for osteoporosis. An entity such as PMS may be an important physiological marker of a calcium disturbance. The purpose of this investigation is to understand more completely the extent to which calcium balance is disturbed in severe PMS or Premenstrual Dysphoric Disorder (PMDD) by utilizing new tools to assess calcium and bone turnover. The long term objective is to elucidate the pathophysiology of PMDD or severe PMS as it relates to calcium hormones and bone markers. The experimental design involves the comparison between women witn severe PMS and asymptomatic controls.

NCT00005119
Principal SponsorNational Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Last updated: March 2, 2010
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.

Diagnostic Study

Diagnostic studies focus on improving how we detect or confirm a disease. They test new tools or techniques that could provide faster or more accurate diagnoses.

Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Conditions
Criteria

Female

Biological sex of participants that are eligible to enroll.

From 18 to 45 Years

Range of ages for which participants are eligible to join.

Healthy volunteers allowed

If individuals who are healthy and do not have the condition being studied can participate.

Conditions

Pathology

Mental DisordersDepressive DisorderMenstruation DisturbancesPathologic ProcessesPathological Conditions, Signs and SymptomsMood DisordersPremenstrual SyndromePremenstrual Dysphoric Disorder

Criteria

7 inclusion criteria required to participate
General good health
Medical history of severe PMS for the PMS group
No history of metabolic bone disease
No medical history of PMS for the control group
Show More Criteria
19 exclusion criteria prevent from participating
Amenorrhea
Anorexia nervosa
Cushing's syndrome
Erosive gastrointestinal disease
Show More Criteria

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 1 location

St. Luke's-Roosevelt Hospital

New York, United StatesOpen St. Luke's-Roosevelt Hospital in Google Maps
CompletedOne Study Center