Genetic and Environmental Risk Factors Analysis in Hispanic Children with Type 2Y Diabetes

This study focuses on a specific form of diabetes called type 2 diabetes of youth, or type 2Y, which is increasingly common in children under 20, particularly those who are obese and belong to certain ethnic groups. The study aims to understand the genetic and environmental risk factors contributing to type 2Y, especially among Hispanic children in the Houston area. The research also seeks to improve care for these patients by exploring the most effective treatment options, as there is currently no consensus on the best approach. The study will review medical records of pediatric diabetes patients at the University of Texas, anticipating around 200 patients with type 1 diabetes and 30 with type 2Y diabetes. A Sustacal challenge test will confirm the clinical diagnosis for suspected type 2Y patients. Researchers will contact parents for a detailed family history and compare type 1 and type 2Y patients based on various factors. Additionally, the study will review the medical records to compare the effectiveness of insulin treatment versus oral agents for type 2Y patients. A subset of patients will also be tested for a gene associated with type 2 diabetes in adult Hispanics.