Suspended

Annual Evaluation of NF2-Related Tumors Growth and Clinical Course in Neurofibromatosis 2 Patients

Study Aim

This study aims to observe the growth of NF2-related tumors and the clinical course in individuals diagnosed with Neurofibromatosis 2, on an annual basis.

What is being collected

Data Collection

Who is being recruted

Vestibulocochlear Nerve Diseases+31

+ Cranial Nerve Diseases

+ Cranial Nerve Neoplasms

Over 5 Years

See all eligibility criteria

How is the trial designed

Natural History

Observing the progression of a disease in untreated individuals in order to understand its typical course and outcomes.

Observational

Study Start: January 2002

See protocol details

Summary

Principal SponsorHouse Ear Institute

Last updated: September 29, 2005

Sourced from a government-validated database.Claim as a partner

Study start date: January 1, 2002

Actual date on which the first participant was enrolled.

PROTOCOL OUTLINE: Data on the clinical course and growth rate of NF2-related tumors in patients with neurofibromatosis 2. Patients are evaluated each year on a cranial and a spinal MRI, eye tests, hearing tests, quality of life, neurological tests, and physical functioning.

NCT00004483

Principal SponsorHouse Ear Institute

Last updated: September 29, 2005

Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.

Design Details

100 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.

Natural History

These studies observe how a disease progresses over time without active treatment. They help researchers understand how conditions typically develop, change, and impact quality of life.

Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.

Conditions

Criteria

Any sex

Biological sex of participants that are eligible to enroll.

Over 5 Years

Range of ages for which participants are eligible to join.

Healthy volunteers not allowed

If individuals who are healthy and do not have the condition being studied can participate.

Conditions

Pathology

Vestibulocochlear Nerve DiseasesCranial Nerve DiseasesCranial Nerve NeoplasmsEar DiseasesMeningeal NeoplasmsCongenital, Hereditary, and Neonatal Diseases and AbnormalitiesNeoplasmsNeoplasms by Histologic TypeNeoplasms by SiteNeoplasms, Germ Cell and EmbryonalNeoplasms, Nerve TissueNeoplasms, Vascular TissueNeoplastic Syndromes, HereditaryNervous System DiseasesNervous System NeoplasmsNeurilemmomaNeurofibromaNeuromaOtorhinolaryngologic DiseasesOtorhinolaryngologic NeoplasmsPeripheral Nervous System NeoplasmsRetrocochlear DiseasesCentral Nervous System NeoplasmsNeurofibromatosesNeuroectodermal TumorsNerve Sheath NeoplasmsNeuroendocrine TumorsNeurodegenerative DiseasesHeredodegenerative Disorders, Nervous SystemNeurocutaneous SyndromesGenetic Diseases, InbornMeningiomaNeuroma, AcousticNeurofibromatosis 2

Criteria

PROTOCOL ENTRY CRITERIA: --Disease Characteristics-- Diagnosed with neurofibromatosis 2 on or after 01/01/93 Must meet one of the following conditions: Bilateral vestibular schwannoma OR Family history of neurofibromatosis 2 (first degree family relative) AND Unilateral vestibular schwannoma at under 30 years OR Any 2 of the following: Meningioma Glioma Schwannoma Juvenile posterior subcapsular lenticular opacity/juvenile cortical cataract No plans to treat vestibular schwannoma in next 12 months --Prior/Concurrent Therapy-- Not specified --Patient Characteristics-- Age: 5 and over

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 1 location

House Ear Institute

Los Angeles, United StatesOpen House Ear Institute in Google Maps

SuspendedOne Study Center