Evaluation of Childhood Disintegrative Disorder through Questionnaires, MRI, EEG, and Genetic Studies
Data Collection
Autism Spectrum Disorder+9
+ Nervous System Diseases
+ Pathologic Processes
Summary
Study start date: May 1, 1997
Actual date on which the first participant was enrolled.PROTOCOL OUTLINE: Patients are evaluated with the following questionnaires at ages 2-3 years and again at ages 5-9: The Autism Diagnostic Interview (ADI); The Autism Diagnostic Observation Schedule (ADOS); Assessment of cognitive functioning; Expressive and receptive language; Adaptive functioning; Measures of burden and functional assessment; The Aberrant Behavior Checklist; The Connors Rating Scale - Parent and Teacher version; and Autism Behavior Checklist An MRI and EEG are performed, and blood samples are collected from patients and family members for molecular genetic studies.
Protocol
This section provides details of the study plan, including how the study is designed and what the study is measuring.220 patients to be enrolled
Total number of participants that the clinical trial aims to recruit.Eligibility
Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.Any sex
Biological sex of participants that are eligible to enroll.From 2 to 9 Years
Range of ages for which participants are eligible to join.Healthy volunteers not allowed
If individuals who are healthy and do not have the condition being studied can participate.Conditions
Pathology
Criteria
Psychologically diagnosed (DSM-IV) as Childhood Disintegrative Disorder No known genetic or medical syndrome (Down syndrome or cerebral palsy) Must speak English
Study Centers
These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.This study has 2 locations
University of Chicago Cancer Research Center
Chicago, United States