Completed
Randomized Study of the Effects of Glucose on Cognition in Healthy Young and Elderly People and Parkinson's Disease Patients
What is being tested
Glucose
Drug
Who is being recruted
Synucleinopathies+13
+ Basal Ganglia Diseases
+ Brain Diseases
Over 18 Years
+3 Eligibility Criteria
How is the trial designed
Treatment Study
Interventional
Study Start: March 1998
Summary
Principal SponsorNational Institute of Mental Health (NIMH)
Last updated: December 1, 2005
Sourced from a government-validated database.Claim as a partner
Study start date: March 1, 1998
Actual date on which the first participant was enrolled.Subjects fast for 8 hours before receiving a test to determine their blood glucose levels. Following this test, subjects are randomized to receive either a glucose or saccharin sweetened drink. A series of memory tests and an additional 3 blood glucose level tests are administered approximately 15 minutes later. A minimum of 1 week afterward, the subjects return and receive the alternate sweetener followed by additional memory tests.
Principal SponsorNational Institute of Mental Health (NIMH)
Last updated: December 1, 2005
Sourced from a government-validated database.Claim as a partner
Protocol
This section provides details of the study plan, including how the study is designed and what the study is measuring.Design Details
120 patients to be enrolled
Total number of participants that the clinical trial aims to recruit.Treatment Study
These studies test new ways to treat a disease, condition, or health issue. The goal is to see if a new drug, therapy, or approach works better or has fewer side effects than existing options.
Eligibility
Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.Conditions
Criteria
Any sex
Biological sex of participants that are eligible to enroll.Over 18 Years
Range of ages for which participants are eligible to join.Healthy volunteers allowed
If individuals who are healthy and do not have the condition being studied can participate.Conditions
Pathology
SynucleinopathiesBasal Ganglia DiseasesBrain DiseasesCentral Nervous System DiseasesMovement DisordersNervous System DiseasesPathologic ProcessesSigns and SymptomsPathological Conditions, Signs and SymptomsNeurodegenerative DiseasesParkinsonian DisordersDisease AttributesMental DisordersNeurologic ManifestationsParkinson DiseaseRare Diseases
Criteria
1 inclusion criteria required to participate
Three groups of subjects are eligible for this study: Healthy young adults between ages 18 and 30; Healthy elderly adults between ages 60 and 90; AND Anyone diagnosed with Parkinson's disease
2 exclusion criteria prevent from participating
Diabetes, Addison's, or Cushing's diseases
Prior surgery to remove part of the stomach
Study Centers
These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.This study has 1 location
CompletedOne Study Center