Study of the Metabolism of Pyruvate and Related Problems in Patients With Lactic Acidemia
Data Collection
Acid-Base Imbalance+25
+ Acidosis
+ Brain Diseases
Summary
Study start date: December 1, 1978
Actual date on which the first participant was enrolled.PROTOCOL OUTLINE: Patients fast for 6 hours. Glucagon IM is administered after the 6 hour fast. Glucose level is measured at 0, 15, 30, 45, 60, and 90 minutes. In children of sufficient size, alanine and lactic acid should also be measured at each or most of these time points. Fasting continues for at least 18 hours. Glucagon IM is administered again at end of fast. Glucose level is measured at time 0, 15, 30, 45, 60, and 90 minutes.
Protocol
This section provides details of the study plan, including how the study is designed and what the study is measuring.35 patients to be enrolled
Total number of participants that the clinical trial aims to recruit.Eligibility
Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.Any sex
Biological sex of participants that are eligible to enroll.Healthy volunteers not allowed
If individuals who are healthy and do not have the condition being studied can participate.Conditions
Pathology
Criteria
PROTOCOL ENTRY CRITERIA: Diagnostically documented elevation in lactate, pyruvate, and/or alanine levels in lactic acidemia patients
Study Centers
These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.This study has 1 location
University of California San Diego Medical Center
San Diego, United StatesOpen University of California San Diego Medical Center in Google Maps