Completed
Comparison of Ro 31-8959 Plus Zidovudine (AZT) Versus AZT Plus Zalcitabine (ddC) Versus Ro 31-8959 Plus AZT Plus ddC
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What is being tested
Saquinavir
+ Zidovudine
+ Zalcitabine
Drug
Who is being recruted
HIV Infections
Over 13 Years
See all eligibility criteria
How is the trial designed
Treatment Study
Phase 2
Interventional
See protocol details
Summary
Principal SponsorHoffmann-La Roche
Last updated: March 1, 2011
Sourced from a government-validated database.Claim as a partner
PRIMARY: To determine the efficacy and toxicity of three treatment regimens: saquinavir mesylate (Ro 31-8959) plus zidovudine (AZT) vs. AZT plus zalcitabine (dideoxycytidine; ddC) vs. Ro 31-8959 plus AZT plus ddC. SECONDARY: To investigate the pharmacokinetics and effects on various clinical parameters of the three regimens.
Principal SponsorHoffmann-La Roche
Last updated: March 1, 2011
Sourced from a government-validated database.Claim as a partner
Protocol
This section provides details of the study plan, including how the study is designed and what the study is measuring.Design Details
300 patients to be enrolledTotal number of participants that the clinical trial aims to recruit.
Treatment Study
These studies test new ways to treat a disease, condition, or health issue. The goal is to see if a new drug, therapy, or approach works better or has fewer side effects than existing options.
Eligibility
Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.Conditions
Criteria
Any sexBiological sex of participants that are eligible to enroll.
Over 13 YearsRange of ages for which participants are eligible to join.
Healthy volunteers not allowedIf individuals who are healthy and do not have the condition being studied can participate.
Conditions
Pathology
HIV Infections
Criteria
Ensure optimum compatibilityAdd your profile to know your probability eligibility score.
Study Centers
These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.This study has 10 locations
Suspended
Suspended
Stanford Univ Med CtrStanford, United States
Suspended
Univ of Colorado Health Sciences CtrDenver, United States
Suspended
Northwestern Univ Med SchoolChicago, United States
Completed10 Study Centers